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Page 1
Early Proteinuria Lowering by Angiotensin-Converting Enzyme Inhibition Predicts Renal Survival in Children with CKD.
van den Belt SM, Heerspink HJL, Gracchi V, de Zeeuw D, Wühl E, Schaefer F; ESCAPE Trial Group. van den Belt SM, et al. J Am Soc Nephrol. 2018 Aug;29(8):2225-2233. doi: 10.1681/ASN.2018010036. Epub 2018 Jun 21. J Am Soc Nephrol. 2018. PMID: 29930161 Free PMC article. Clinical Trial.
Background Although pharmacotherapeutic proteinuria lowering was found to be nephroprotective in adults, the predictive value of early drug-induced proteinuria reduction for long-term renal survival in pediatric CKD is unknown. We analyzed data from the ESCAPE Trial for a …
Background Although pharmacotherapeutic proteinuria lowering was found to be nephroprotective in adults, the predictive value of early drug- …
Long-term growth hormone treatment in short children with CKD does not accelerate decline of renal function: results from the KIGS registry and ESCAPE trial.
Mehls O, Lindberg A, Haffner D, Schaefer F, Wühl E; German KIGS Board; ESCAPE Trial Group. Mehls O, et al. Pediatr Nephrol. 2015 Dec;30(12):2145-51. doi: 10.1007/s00467-015-3157-8. Epub 2015 Jul 22. Pediatr Nephrol. 2015. PMID: 26198275 Clinical Trial.
BACKGROUND: Recombinant human (rh) growth hormone (GH) raises the glomerular filtration rate (GFR) in healthy individuals. Concern has been raised that long-term rhGH treatment in short children with chronic kidney disease (CKD) may accelerate the progression of CKD via in …
BACKGROUND: Recombinant human (rh) growth hormone (GH) raises the glomerular filtration rate (GFR) in healthy individuals. Concern has been …
Long-term side effects of treatment with mTOR inhibitors in children after renal transplantation.
Kranz B, Wingen AM, Vester U, König J, Hoyer PF. Kranz B, et al. Among authors: wingen am. Pediatr Nephrol. 2013 Aug;28(8):1293-8. doi: 10.1007/s00467-013-2459-y. Epub 2013 Apr 13. Pediatr Nephrol. 2013. PMID: 23584849
The aim of this study was to look for long-term side effects of mTORI therapy in pRTx. PATIENTS AND METHODS: The retrospective analysis focused on side effects, growth, and pubertal development under mTORI therapy in 31 children. ...Only one patient experienced cytomegaly …
The aim of this study was to look for long-term side effects of mTORI therapy in pRTx. PATIENTS AND METHODS: The retrospective analys …
Prevalence of hepatitis E virus infection in pediatric solid organ transplant recipients--a single-center experience.
Hoerning A, Hegen B, Wingen AM, Cetiner M, Lainka E, Kathemann S, Fiedler M, Timm J, Wenzel JJ, Hoyer PF, Gerner P. Hoerning A, et al. Among authors: wingen am. Pediatr Transplant. 2012 Nov;16(7):742-7. doi: 10.1111/j.1399-3046.2012.01740.x. Epub 2012 Jun 28. Pediatr Transplant. 2012. PMID: 22738211
The prevalence of HEV infection in pediatric renal or liver transplant recipients is not higher compared with immunocompetent children. Chronic HEV infection with long-term carriage of the virus may develop in pediatric transplant recipients. Autochthonous HEV infection ne …
The prevalence of HEV infection in pediatric renal or liver transplant recipients is not higher compared with immunocompetent children. Chro …
Continuous venovenous haemodialysis (CVVHD) and continuous peritoneal dialysis (CPD) in the acute management of 21 children with inborn errors of metabolism.
Arbeiter AK, Kranz B, Wingen AM, Bonzel KE, Dohna-Schwake C, Hanssler L, Neudorf U, Hoyer PF, Büscher R. Arbeiter AK, et al. Among authors: wingen am. Nephrol Dial Transplant. 2010 Apr;25(4):1257-65. doi: 10.1093/ndt/gfp595. Epub 2009 Nov 23. Nephrol Dial Transplant. 2010. PMID: 19934086
CONCLUSION: CVVHD effectively and quickly eliminates plasma ammonia. To optimize long-term mental outcome, rapid identification and appropriate treatment of the underlying disease as well as starting dialysis early are of enormous therapeutic value....
CONCLUSION: CVVHD effectively and quickly eliminates plasma ammonia. To optimize long-term mental outcome, rapid identification and a …
Strict blood-pressure control and progression of renal failure in children.
ESCAPE Trial Group; Wühl E, Trivelli A, Picca S, Litwin M, Peco-Antic A, Zurowska A, Testa S, Jankauskiene A, Emre S, Caldas-Afonso A, Anarat A, Niaudet P, Mir S, Bakkaloglu A, Enke B, Montini G, Wingen AM, Sallay P, Jeck N, Berg U, Caliskan S, Wygoda S, Hohbach-Hohenfellner K, Dusek J, Urasinski T, Arbeiter K, Neuhaus T, Gellermann J, Drozdz D, Fischbach M, Möller K, Wigger M, Peruzzi L, Mehls O, Schaefer F. ESCAPE Trial Group, et al. Among authors: wingen am. N Engl J Med. 2009 Oct 22;361(17):1639-50. doi: 10.1056/NEJMoa0902066. N Engl J Med. 2009. PMID: 19846849 Free article. Clinical Trial.
BACKGROUND: Although inhibition of the renin-angiotensin system delays the progression of renal failure in adults with chronic kidney disease, the blood-pressure target for optimal renal protection is controversial. We assessed the long-term renoprotective effect of intens …
BACKGROUND: Although inhibition of the renin-angiotensin system delays the progression of renal failure in adults with chronic kidney diseas …
Acute rejection episodes in pediatric renal transplant recipients with cytomegalovirus infection.
Kranz B, Vester U, Wingen AM, Nadalin S, Paul A, Broelsch CE, Hoyer PF. Kranz B, et al. Among authors: wingen am. Pediatr Transplant. 2008 Jun;12(4):474-8. doi: 10.1111/j.1399-3046.2007.00781.x. Pediatr Transplant. 2008. PMID: 18466436
The potential impact of prophylactic anti-viral therapy on long-term graft outcome is relevant. The aim of this study was to evaluate the incidence of CMV infection, its risk factors and long-term outcome in children after renal transplantation. 103 children (mean a …
The potential impact of prophylactic anti-viral therapy on long-term graft outcome is relevant. The aim of this study was to evaluate …
Cyclosporine-A-induced nephrotoxicity in children with minimal-change nephrotic syndrome: long-term treatment up to 10 years.
Kranz B, Vester U, Büscher R, Wingen AM, Hoyer PF. Kranz B, et al. Among authors: wingen am. Pediatr Nephrol. 2008 Apr;23(4):581-6. doi: 10.1007/s00467-007-0709-6. Epub 2008 Jan 16. Pediatr Nephrol. 2008. PMID: 18197423 Free PMC article.
The impact of cyclosporine A (CsA) therapy in patients with steroid-dependent nephrotic-syndrome (SDNS) on long-term renal function is controversial. Data beyond 5 years are rare. Long-term renal function was evaluated in children with SDNS with and without CsA ther …
The impact of cyclosporine A (CsA) therapy in patients with steroid-dependent nephrotic-syndrome (SDNS) on long-term renal function i …
Development of growth and body mass index after pediatric renal transplantation.
Vester U, Schaefer A, Kranz B, Wingen AM, Nadalin S, Paul A, Malagò M, Broelsch CE, Hoyer PF. Vester U, et al. Among authors: wingen am. Pediatr Transplant. 2005 Aug;9(4):445-9. doi: 10.1111/j.1399-3046.2005.00304.x. Pediatr Transplant. 2005. PMID: 16048595
However, genetic or environmental factors predict the long-term weight development....
However, genetic or environmental factors predict the long-term weight development....
Growth and weight gain in children with vesicoureteral reflux receiving medical versus surgical treatment: 10-year results of a prospective, randomized study. International Reflux Study in Children (European Branch).
Wingen AM, Koskimies O, Olbing H, Seppänen J, Tamminen-Möbius T. Wingen AM, et al. Acta Paediatr. 1999 Jan;88(1):56-61. doi: 10.1080/08035259950170619. Acta Paediatr. 1999. PMID: 10090549 Clinical Trial.
A controlled trial comparing the effect on growth of surgical treatment and long-term prophylactic antibiotic treatment has not been reported previously. Between 1980 and 1985, 306 children younger than 11 y with non-obstructive grade III or IV VUR, with a history of sympt …
A controlled trial comparing the effect on growth of surgical treatment and long-term prophylactic antibiotic treatment has not been …
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