Nangle LA - Search Results

1

Enlarging the amino acid set of Escherichia coli by infiltration of the valine coding pathway.

Döring V, Mootz HD, Nangle LA, Hendrickson TL, de Crécy-Lagard V, Schimmel P, Marlière P. Döring V, et al. Among authors: nangle la. Science. 2001 Apr 20;292(5516):501-4. doi: 10.1126/science.1057718. Science. 2001. PMID: 11313495

2

Genetic code ambiguity. Cell viability related to the severity of editing defects in mutant tRNA synthetases.

Nangle LA, De Crecy Lagard V, Doring V, Schimmel P. Nangle LA, et al. J Biol Chem. 2002 Nov 29;277(48):45729-33. doi: 10.1074/jbc.M208093200. Epub 2002 Sep 18. J Biol Chem. 2002. PMID: 12244062 Free article.

3

Global effects of mistranslation from an editing defect in mammalian cells.

Nangle LA, Motta CM, Schimmel P. Nangle LA, et al. Chem Biol. 2006 Oct;13(10):1091-100. doi: 10.1016/j.chembiol.2006.08.011. Chem Biol. 2006. PMID: 17052613

4

Human tRNA synthetase catalytic nulls with diverse functions.

Lo WS, Gardiner E, Xu Z, Lau CF, Wang F, Zhou JJ, Mendlein JD, Nangle LA, Chiang KP, Yang XL, Au KF, Wong WH, Guo M, Zhang M, Schimmel P. Lo WS, et al. Among authors: nangle la. Science. 2014 Jul 18;345(6194):328-32. doi: 10.1126/science.1252943. Science. 2014. PMID: 25035493 Free PMC article.

5

Long-range structural effects of a Charcot-Marie-Tooth disease-causing mutation in human glycyl-tRNA synthetase.

Xie W, Nangle LA, Zhang W, Schimmel P, Yang XL. Xie W, et al. Among authors: nangle la. Proc Natl Acad Sci U S A. 2007 Jun 12;104(24):9976-81. doi: 10.1073/pnas.0703908104. Epub 2007 Jun 1. Proc Natl Acad Sci U S A. 2007. PMID: 17545306 Free PMC article.

6

Charcot-Marie-Tooth disease-associated mutant tRNA synthetases linked to altered dimer interface and neurite distribution defect.

Nangle LA, Zhang W, Xie W, Yang XL, Schimmel P. Nangle LA, et al. Proc Natl Acad Sci U S A. 2007 Jul 3;104(27):11239-44. doi: 10.1073/pnas.0705055104. Epub 2007 Jun 26. Proc Natl Acad Sci U S A. 2007. PMID: 17595294 Free PMC article.

7

Editing-defective tRNA synthetase causes protein misfolding and neurodegeneration.

Lee JW, Beebe K, Nangle LA, Jang J, Longo-Guess CM, Cook SA, Davisson MT, Sundberg JP, Schimmel P, Ackerman SL. Lee JW, et al. Among authors: nangle la. Nature. 2006 Sep 7;443(7107):50-5. doi: 10.1038/nature05096. Epub 2006 Aug 13. Nature. 2006. PMID: 16906134

8

Deficiencies in tRNA synthetase editing activity cause cardioproteinopathy.

Liu Y, Satz JS, Vo MN, Nangle LA, Schimmel P, Ackerman SL. Liu Y, et al. Among authors: nangle la. Proc Natl Acad Sci U S A. 2014 Dec 9;111(49):17570-5. doi: 10.1073/pnas.1420196111. Epub 2014 Nov 24. Proc Natl Acad Sci U S A. 2014. PMID: 25422440 Free PMC article.

9

An active dominant mutation of glycyl-tRNA synthetase causes neuropathy in a Charcot-Marie-Tooth 2D mouse model.

Seburn KL, Nangle LA, Cox GA, Schimmel P, Burgess RW. Seburn KL, et al. Among authors: nangle la. Neuron. 2006 Sep 21;51(6):715-26. doi: 10.1016/j.neuron.2006.08.027. Neuron. 2006. PMID: 16982418 Free article.

10

Orthogonal use of a human tRNA synthetase active site to achieve multifunctionality.

Zhou Q, Kapoor M, Guo M, Belani R, Xu X, Kiosses WB, Hanan M, Park C, Armour E, Do MH, Nangle LA, Schimmel P, Yang XL. Zhou Q, et al. Among authors: nangle la. Nat Struct Mol Biol. 2010 Jan;17(1):57-61. doi: 10.1038/nsmb.1706. Epub 2009 Dec 13. Nat Struct Mol Biol. 2010. PMID: 20010843 Free PMC article.

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