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Primary hyperparathyroidism caused by parathyroid-targeted overexpression of cyclin D1 in transgenic mice.
Imanishi Y, Hosokawa Y, Yoshimoto K, Schipani E, Mallya S, Papanikolaou A, Kifor O, Tokura T, Sablosky M, Ledgard F, Gronowicz G, Wang TC, Schmidt EV, Hall C, Brown EM, Bronson R, Arnold A. Imanishi Y, et al. Among authors: ledgard f. J Clin Invest. 2001 May;107(9):1093-102. doi: 10.1172/JCI10523. J Clin Invest. 2001. PMID: 11342573 Free PMC article.
Do cyclooxygenase-2 knockout mice have primary hyperparathyroidism?
Xu M, Choudhary S, Goltzman D, Ledgard F, Adams D, Gronowicz G, Koczon-Jaremko B, Raisz L, Pilbeam C. Xu M, et al. Among authors: ledgard f. Endocrinology. 2005 Apr;146(4):1843-53. doi: 10.1210/en.2004-0734. Epub 2004 Dec 29. Endocrinology. 2005. PMID: 15625247
Alendronate treatment of the brtl osteogenesis imperfecta mouse improves femoral geometry and load response before fracture but decreases predicted material properties and has detrimental effects on osteoblasts and bone formation.
Uveges TE, Kozloff KM, Ty JM, Ledgard F, Raggio CL, Gronowicz G, Goldstein SA, Marini JC. Uveges TE, et al. Among authors: ledgard f. J Bone Miner Res. 2009 May;24(5):849-59. doi: 10.1359/jbmr.081238. J Bone Miner Res. 2009. PMID: 19113917 Free PMC article.