Galitsky N - Search Results

1

Structure of the insecticidal bacterial delta-endotoxin Cry3Bb1 of Bacillus thuringiensis.

Galitsky N, Cody V, Wojtczak A, Ghosh D, Luft JR, Pangborn W, English L. Galitsky N, et al. Acta Crystallogr D Biol Crystallogr. 2001 Aug;57(Pt 8):1101-9. doi: 10.1107/s0907444901008186. Epub 2001 Jul 23. Acta Crystallogr D Biol Crystallogr. 2001. PMID: 11468393

2

Structure-based enzyme inhibitor design: modeling studies and crystal structure analysis of Pneumocystis carinii dihydrofolate reductase ternary complex with PT653 and NADPH.

Cody V, Galitsky N, Luft JR, Pangborn W, Rosowsky A, Queener SF. Cody V, et al. Among authors: galitsky n. Acta Crystallogr D Biol Crystallogr. 2002 Jun;58(Pt 6 Pt 2):946-54. doi: 10.1107/s090744490200505x. Epub 2002 May 29. Acta Crystallogr D Biol Crystallogr. 2002. PMID: 12037296

3

Analysis of quinazoline and pyrido[2,3-d]pyrimidine N9-C10 reversed-bridge antifolates in complex with NADP+ and Pneumocystis carinii dihydrofolate reductase.

Cody V, Galitsky N, Luft JR, Pangborn W, Queener SF, Gangjee A. Cody V, et al. Among authors: galitsky n. Acta Crystallogr D Biol Crystallogr. 2002 Sep;58(Pt 9):1393-9. doi: 10.1107/S0907444902010442. Epub 2002 Aug 23. Acta Crystallogr D Biol Crystallogr. 2002. PMID: 12198294

4

Analysis of two polymorphic forms of a pyrido[2,3-d]pyrimidine N9-C10 reversed-bridge antifolate binary complex with human dihydrofolate reductase.

Cody V, Galitsky N, Luft JR, Pangborn W, Gangjee A. Cody V, et al. Among authors: galitsky n. Acta Crystallogr D Biol Crystallogr. 2003 Apr;59(Pt 4):654-61. doi: 10.1107/s0907444903001951. Epub 2003 Mar 25. Acta Crystallogr D Biol Crystallogr. 2003. PMID: 12657784

5

Comparison of ternary complexes of Pneumocystis carinii and wild-type human dihydrofolate reductase with coenzyme NADPH and a novel classical antitumor furo[2,3-d]pyrimidine antifolate.

Cody V, Galitsky N, Luft JR, Pangborn W, Gangjee A, Devraj R, Queener SF, Blakley RL. Cody V, et al. Among authors: galitsky n. Acta Crystallogr D Biol Crystallogr. 1997 Nov 1;53(Pt 6):638-49. doi: 10.1107/S090744499700509X. Acta Crystallogr D Biol Crystallogr. 1997. PMID: 15299851

6

Comparison of two independent crystal structures of human dihydrofolate reductase ternary complexes reduced with nicotinamide adenine dinucleotide phosphate and the very tight-binding inhibitor PT523.

Cody V, Galitsky N, Luft JR, Pangborn W, Rosowsky A, Blakley RL. Cody V, et al. Among authors: galitsky n. Biochemistry. 1997 Nov 11;36(45):13897-903. doi: 10.1021/bi971711l. Biochemistry. 1997. PMID: 9374868

7

Comparison of ternary crystal complexes of F31 variants of human dihydrofolate reductase with NADPH and a classical antitumor furopyrimidine.

Cody V, Galitsky N, Luft JR, Pangborn W, Blakley RL, Gangjee A. Cody V, et al. Among authors: galitsky n. Anticancer Drug Des. 1998 Jun;13(4):307-15. Anticancer Drug Des. 1998. PMID: 9627670

8

Ligand-induced conformational changes in the crystal structures of Pneumocystis carinii dihydrofolate reductase complexes with folate and NADP+.

Cody V, Galitsky N, Rak D, Luft JR, Pangborn W, Queener SF. Cody V, et al. Among authors: galitsky n. Biochemistry. 1999 Apr 6;38(14):4303-12. doi: 10.1021/bi982728m. Biochemistry. 1999. PMID: 10194348

9

Structural studies on bioactive compounds. 30. Crystal structure and molecular modeling studies on the Pneumocystis carinii dihydrofolate reductase cofactor complex with TAB, a highly selective antifolate.

Cody V, Chan D, Galitsky N, Rak D, Luft JR, Pangborn W, Queener SF, Laughton CA, Stevens MF. Cody V, et al. Among authors: galitsky n. Biochemistry. 2000 Apr 4;39(13):3556-64. doi: 10.1021/bi9924563. Biochemistry. 2000. PMID: 10736154

10

Methotrexate-resistant variants of human dihydrofolate reductase with substitutions of leucine 22. Kinetics, crystallography, and potential as selectable markers.

Lewis WS, Cody V, Galitsky N, Luft JR, Pangborn W, Chunduru SK, Spencer HT, Appleman JR, Blakley RL. Lewis WS, et al. Among authors: galitsky n. J Biol Chem. 1995 Mar 10;270(10):5057-64. doi: 10.1074/jbc.270.10.5057. J Biol Chem. 1995. PMID: 7890613 Free article.

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