Caron PR - Search Results

1

A mutational analysis of the active site of human type II inosine 5'-monophosphate dehydrogenase.

Futer O, Sintchak MD, Caron PR, Nimmesgern E, DeCenzo MT, Livingston DJ, Raybuck SA. Futer O, et al. Among authors: caron pr. Biochim Biophys Acta. 2002 Jan 31;1594(1):27-39. doi: 10.1016/s0167-4838(01)00277-1. Biochim Biophys Acta. 2002. PMID: 11825606

2

Structure and mechanism of inosine monophosphate dehydrogenase in complex with the immunosuppressant mycophenolic acid.

Sintchak MD, Fleming MA, Futer O, Raybuck SA, Chambers SP, Caron PR, Murcko MA, Wilson KP. Sintchak MD, et al. Among authors: caron pr. Cell. 1996 Jun 14;85(6):921-30. doi: 10.1016/s0092-8674(00)81275-1. Cell. 1996. PMID: 8681386 Free article.

3

X-ray structure of calcineurin inhibited by the immunophilin-immunosuppressant FKBP12-FK506 complex.

Griffith JP, Kim JL, Kim EE, Sintchak MD, Thomson JA, Fitzgibbon MJ, Fleming MA, Caron PR, Hsiao K, Navia MA. Griffith JP, et al. Among authors: caron pr. Cell. 1995 Aug 11;82(3):507-22. doi: 10.1016/0092-8674(95)90439-5. Cell. 1995. PMID: 7543369 Free article.

4

CORES: an automated method for generating three-dimensional models of protein/ligand complexes.

Hare BJ, Walters WP, Caron PR, Bemis GW. Hare BJ, et al. Among authors: caron pr. J Med Chem. 2004 Sep 9;47(19):4731-40. doi: 10.1021/jm0499054. J Med Chem. 2004. PMID: 15341488

5

Peptide sequencing and site-directed mutagenesis identify tyrosine-727 as the active site tyrosine of Saccharomyces cerevisiae DNA topoisomerase I.

Lynn RM, Bjornsti MA, Caron PR, Wang JC. Lynn RM, et al. Among authors: caron pr. Proc Natl Acad Sci U S A. 1989 May;86(10):3559-63. doi: 10.1073/pnas.86.10.3559. Proc Natl Acad Sci U S A. 1989. PMID: 2542938 Free PMC article.

6

Crystal structure of p38 mitogen-activated protein kinase.

Wilson KP, Fitzgibbon MJ, Caron PR, Griffith JP, Chen W, McCaffrey PG, Chambers SP, Su MS. Wilson KP, et al. Among authors: caron pr. J Biol Chem. 1996 Nov 1;271(44):27696-700. doi: 10.1074/jbc.271.44.27696. J Biol Chem. 1996. PMID: 8910361 Free article.

7

Hepatitis C virus NS3 RNA helicase domain with a bound oligonucleotide: the crystal structure provides insights into the mode of unwinding.

Kim JL, Morgenstern KA, Griffith JP, Dwyer MD, Thomson JA, Murcko MA, Lin C, Caron PR. Kim JL, et al. Among authors: caron pr. Structure. 1998 Jan 15;6(1):89-100. doi: 10.1016/s0969-2126(98)00010-0. Structure. 1998. PMID: 9493270 Free article.

8

Crystal structure of JNK3: a kinase implicated in neuronal apoptosis.

Xie X, Gu Y, Fox T, Coll JT, Fleming MA, Markland W, Caron PR, Wilson KP, Su MS. Xie X, et al. Among authors: caron pr. Structure. 1998 Aug 15;6(8):983-91. doi: 10.1016/s0969-2126(98)00100-2. Structure. 1998. PMID: 9739089 Free article.

9

The structural basis for the specificity of pyridinylimidazole inhibitors of p38 MAP kinase.

Wilson KP, McCaffrey PG, Hsiao K, Pazhanisamy S, Galullo V, Bemis GW, Fitzgibbon MJ, Caron PR, Murcko MA, Su MS. Wilson KP, et al. Among authors: caron pr. Chem Biol. 1997 Jun;4(6):423-31. doi: 10.1016/s1074-5521(97)90194-0. Chem Biol. 1997. PMID: 9224565

10

Chemogenomic approaches to drug discovery.

Caron PR, Mullican MD, Mashal RD, Wilson KP, Su MS, Murcko MA. Caron PR, et al. Curr Opin Chem Biol. 2001 Aug;5(4):464-70. doi: 10.1016/s1367-5931(00)00229-5. Curr Opin Chem Biol. 2001. PMID: 11470611 Review. No abstract available.

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