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Alterations in thin filament regulation induced by a human cardiac troponin T mutant that causes dilated cardiomyopathy are distinct from those induced by troponin T mutants that cause hypertrophic cardiomyopathy.
Robinson P, Mirza M, Knott A, Abdulrazzak H, Willott R, Marston S, Watkins H, Redwood C. Robinson P, et al. Among authors: knott a. J Biol Chem. 2002 Oct 25;277(43):40710-6. doi: 10.1074/jbc.M203446200. Epub 2002 Aug 18. J Biol Chem. 2002. PMID: 12186860 Free article.
Investigation of a truncated cardiac troponin T that causes familial hypertrophic cardiomyopathy: Ca(2+) regulatory properties of reconstituted thin filaments depend on the ratio of mutant to wild-type protein.
Redwood C, Lohmann K, Bing W, Esposito GM, Elliott K, Abdulrazzak H, Knott A, Purcell I, Marston S, Watkins H. Redwood C, et al. Among authors: knott a. Circ Res. 2000 Jun 9;86(11):1146-52. doi: 10.1161/01.res.86.11.1146. Circ Res. 2000. PMID: 10850966
Clinical epidemiology of COVID-19 in people of black ethnicity living with HIV in the UK.
Ottaway Z, Campbell L, Cechin LR, Patel N, Fox J, Burns F, Hamzah L, Kegg S, Rosenvinge M, Schoeman S, Price D, Jones R, Clarke A, Maan I, Ustianowski A, Onyango D, Tariq S, Miller RF, Post FA; COVID‐AFRICA study group. Ottaway Z, et al. HIV Med. 2024 May;25(5):614-621. doi: 10.1111/hiv.13611. Epub 2024 Jan 11. HIV Med. 2024. PMID: 38213094
Real-World First-Line Use of Pertuzumab With Different Taxanes for Human Epidermal Growth Factor Receptor 2-Positive Metastatic Breast Cancer: A Comparative Effectiveness Study Using US Electronic Health Records.
Polito L, Shim J, Hurvitz SA, Dang CT, Knott A, Du Toit Y, Restuccia E, Sanglier T, Swain SM. Polito L, et al. Among authors: knott a. JCO Oncol Pract. 2023 Jul;19(7):435-445. doi: 10.1200/OP.22.00565. Epub 2023 May 11. JCO Oncol Pract. 2023. PMID: 37167571 Free PMC article.
Developing SHP2-based combination therapy for KRAS-amplified cancer.
Li T, Kikuchi O, Zhou J, Wang Y, Pokharel B, Bastl K, Gokhale P, Knott A, Zhang Y, Doench JG, Ho ZV, Catenacci DV, Bass AJ. Li T, et al. Among authors: knott a. JCI Insight. 2023 Feb 8;8(3):e152714. doi: 10.1172/jci.insight.152714. JCI Insight. 2023. PMID: 36752207 Free PMC article.
Pertuzumab, trastuzumab, and docetaxel for Chinese patients with previously untreated HER2-positive locally recurrent or metastatic breast cancer (PUFFIN): final analysis of a phase III, randomized, double-blind, placebo-controlled study.
Xu B, Li W, Zhang Q, Li Q, Wang X, Li H, Sun T, Yin Y, Zheng H, Feng J, Zhu H, Siddiqui A, Macharia H, Knott A. Xu B, et al. Among authors: knott a. Breast Cancer Res Treat. 2023 Feb;197(3):503-513. doi: 10.1007/s10549-022-06775-1. Epub 2022 Dec 4. Breast Cancer Res Treat. 2023. PMID: 36463547 Free PMC article. Clinical Trial.
148 results