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Ikaros is critical for B cell differentiation and function.
Kirstetter P, Thomas M, Dierich A, Kastner P, Chan S. Kirstetter P, et al. Among authors: thomas m. Eur J Immunol. 2002 Mar;32(3):720-30. doi: 10.1002/1521-4141(200203)32:3<720::AID-IMMU720>3.0.CO;2-P. Eur J Immunol. 2002. PMID: 11870616 Free article.
Upstream elements involved in vivo in activation of the brain-specific rat aldolase C gene. Role of binding sites for POU and winged helix proteins.
Skala H, Porteu A, Thomas M, Szajnert MF, Okazawa H, Kahn A, Phan-Dinh-Tuy F. Skala H, et al. Among authors: thomas m. J Biol Chem. 1998 Nov 27;273(48):31806-14. doi: 10.1074/jbc.273.48.31806. J Biol Chem. 1998. PMID: 9822647 Free article.
We previously reported that a 115-base pair (bp) promoter fragment was able to ensure the brain-specific expression of the chloramphenicol acetyltransferase (CAT) reporter gene in transgenic mice, but only at a low level (Thomas, M., Makeh, I., Briand, P., Kahn, A., …
We previously reported that a 115-base pair (bp) promoter fragment was able to ensure the brain-specific expression of the chloramphenicol a …
Functional dissection of the brain-specific rat aldolase C gene promoter in transgenic mice. Essential role of two GC-rich boxes and an HNF3 binding site.
Thomas M, Skala H, Kahn A, Tuy FP. Thomas M, et al. J Biol Chem. 1995 Sep 1;270(35):20316-21. doi: 10.1074/jbc.270.35.20316. J Biol Chem. 1995. PMID: 7657603 Free article.
Both A/A' and B boxes, sharing structural homology, are able to interact with Sp1, Krox20/Krox24 factors and with other proteins (Thomas, M., Makeh, I., Briand, P., Kahn, A., and Skala, H. (1993) Eur. ...
Both A/A' and B boxes, sharing structural homology, are able to interact with Sp1, Krox20/Krox24 factors and with other proteins (Thomas …
Mixed responses to targeted therapy driven by chromosomal instability through p53 dysfunction and genome doubling.
Hobor S, Al Bakir M, Hiley CT, Skrzypski M, Frankell AM, Bakker B, Watkins TBK, Markovets A, Dry JR, Brown AP, van der Aart J, van den Bos H, Spierings D, Oukrif D, Novelli M, Chakrabarti T, Rabinowitz AH, Ait Hassou L, Litière S, Kerr DL, Tan L, Kelly G, Moore DA, Renshaw MJ, Venkatesan S, Hill W, Huebner A, Martínez-Ruiz C, Black JRM, Wu W, Angelova M, McGranahan N, Downward J, Chmielecki J, Barrett C, Litchfield K, Chew SK, Blakely CM, de Bruin EC, Foijer F, Vousden KH, Bivona TG; TRACERx consortium; Hynds RE, Kanu N, Zaccaria S, Grönroos E, Swanton C. Hobor S, et al. Nat Commun. 2024 Jun 13;15(1):4871. doi: 10.1038/s41467-024-47606-9. Nat Commun. 2024. PMID: 38871738 Free PMC article.
KRAS and TP53 co-mutation predicts benefit of immune checkpoint blockade in lung adenocarcinoma.
Budczies J, Romanovsky E, Kirchner M, Neumann O, Blasi M, Schnorbach J, Shah R, Bozorgmehr F, Savai R, Stiewe T, Peters S, Schirmacher P, Thomas M, Kazdal D, Christopoulos P, Stenzinger A. Budczies J, et al. Among authors: thomas m. Br J Cancer. 2024 Jun 12. doi: 10.1038/s41416-024-02746-z. Online ahead of print. Br J Cancer. 2024. PMID: 38866964
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