Hakeda Y - Search Results

1

Regulation of receptor activator of NF-kappa B ligand-induced osteoclastogenesis by endogenous interferon-beta (INF-beta ) and suppressors of cytokine signaling (SOCS). The possible counteracting role of SOCSs- in IFN-beta-inhibited osteoclast formation.

Hayashi T, Kaneda T, Toyama Y, Kumegawa M, Hakeda Y. Hayashi T, et al. Among authors: hakeda y. J Biol Chem. 2002 Aug 2;277(31):27880-6. doi: 10.1074/jbc.M203836200. Epub 2002 May 22. J Biol Chem. 2002. PMID: 12023971 Free article.

2

Dexamethasone enhances osteoclast formation synergistically with transforming growth factor-beta by stimulating the priming of osteoclast progenitors for differentiation into osteoclasts.

Takuma A, Kaneda T, Sato T, Ninomiya S, Kumegawa M, Hakeda Y. Takuma A, et al. Among authors: hakeda y. J Biol Chem. 2003 Nov 7;278(45):44667-74. doi: 10.1074/jbc.M300213200. Epub 2003 Aug 27. J Biol Chem. 2003. PMID: 12944401 Free article.

3

The active metabolite of leflunomide, A771726, inhibits both the generation of and the bone-resorbing activity of osteoclasts by acting directly on cells of the osteoclast lineage.

Kobayashi Y, Ueyama S, Arai Y, Yoshida Y, Kaneda T, Sato T, Shin K, Kumegawa M, Hakeda Y. Kobayashi Y, et al. Among authors: hakeda y. J Bone Miner Metab. 2004;22(4):318-28. doi: 10.1007/s00774-003-0489-4. J Bone Miner Metab. 2004. PMID: 15221489

4

Receptor activator of NF-κB ligand-dependent expression of caveolin-1 in osteoclast precursors, and high dependency of osteoclastogenesis on exogenous lipoprotein.

Hada N, Okayasu M, Ito J, Nakayachi M, Hayashida C, Kaneda T, Uchida N, Muramatsu T, Koike C, Masuhara M, Sato T, Hakeda Y. Hada N, et al. Among authors: hakeda y. Bone. 2012 Jan;50(1):226-36. doi: 10.1016/j.bone.2011.10.028. Epub 2011 Oct 30. Bone. 2012. PMID: 22075210

5

Low-density lipoprotein receptor deficiency causes impaired osteoclastogenesis and increased bone mass in mice because of defect in osteoclastic cell-cell fusion.

Okayasu M, Nakayachi M, Hayashida C, Ito J, Kaneda T, Masuhara M, Suda N, Sato T, Hakeda Y. Okayasu M, et al. Among authors: hakeda y. J Biol Chem. 2012 Jun 1;287(23):19229-41. doi: 10.1074/jbc.M111.323600. Epub 2012 Apr 12. J Biol Chem. 2012. PMID: 22500026 Free PMC article.

6

Cloning and function of rabbit peroxisome proliferator-activated receptor delta/beta in mature osteoclasts.

Mano H, Kimura C, Fujisawa Y, Kameda T, Watanabe-Mano M, Kaneko H, Kaneda T, Hakeda Y, Kumegawa M. Mano H, et al. Among authors: hakeda y. J Biol Chem. 2000 Mar 17;275(11):8126-32. doi: 10.1074/jbc.275.11.8126. J Biol Chem. 2000. PMID: 10713135 Free article.

7

Endogenous production of TGF-beta is essential for osteoclastogenesis induced by a combination of receptor activator of NF-kappa B ligand and macrophage-colony-stimulating factor.

Kaneda T, Nojima T, Nakagawa M, Ogasawara A, Kaneko H, Sato T, Mano H, Kumegawa M, Hakeda Y. Kaneda T, et al. Among authors: hakeda y. J Immunol. 2000 Oct 15;165(8):4254-63. doi: 10.4049/jimmunol.165.8.4254. J Immunol. 2000. PMID: 11035059

8

Mechanism of stimulation of osteoclastic bone resorption through Gas6/Tyro 3, a receptor tyrosine kinase signaling, in mouse osteoclasts.

Katagiri M, Hakeda Y, Chikazu D, Ogasawara T, Takato T, Kumegawa M, Nakamura K, Kawaguchi H. Katagiri M, et al. Among authors: hakeda y. J Biol Chem. 2001 Mar 9;276(10):7376-82. doi: 10.1074/jbc.M007393200. Epub 2000 Nov 17. J Biol Chem. 2001. PMID: 11084030 Free article.

9

Fluid shear stress-induced cyclooxygenase-2 expression is mediated by C/EBP beta, cAMP-response element-binding protein, and AP-1 in osteoblastic MC3T3-E1 cells.

Ogasawara A, Arakawa T, Kaneda T, Takuma T, Sato T, Kaneko H, Kumegawa M, Hakeda Y. Ogasawara A, et al. Among authors: hakeda y. J Biol Chem. 2001 Mar 9;276(10):7048-54. doi: 10.1074/jbc.M008070200. Epub 2000 Nov 22. J Biol Chem. 2001. PMID: 11092885 Free article.

10

Lectin-like oxidized low-density lipoprotein receptor-1 abrogation causes resistance to inflammatory bone destruction in mice, despite promoting osteoclastogenesis in the steady state.

Nakayachi M, Ito J, Hayashida C, Ohyama Y, Kakino A, Okayasu M, Sato T, Ogasawara T, Kaneda T, Suda N, Sawamura T, Hakeda Y. Nakayachi M, et al. Among authors: hakeda y. Bone. 2015 Jun;75:170-82. doi: 10.1016/j.bone.2015.02.025. Epub 2015 Mar 2. Bone. 2015. PMID: 25744064

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