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Entecavir for the treatment of chronic hepatitis B.
Shaw T, Locarnini S. Shaw T, et al. Among authors: locarnini s. Expert Rev Anti Infect Ther. 2004 Dec;2(6):853-71. doi: 10.1586/14789072.2.6.853. Expert Rev Anti Infect Ther. 2004. PMID: 15566330 Review.
The L80I substitution in the reverse transcriptase domain of the hepatitis B virus polymerase is associated with lamivudine resistance and enhanced viral replication in vitro.
Warner N, Locarnini S, Kuiper M, Bartholomeusz A, Ayres A, Yuen L, Shaw T. Warner N, et al. Among authors: locarnini s. Antimicrob Agents Chemother. 2007 Jul;51(7):2285-92. doi: 10.1128/AAC.01499-06. Epub 2007 Apr 16. Antimicrob Agents Chemother. 2007. PMID: 17438047 Free PMC article.
HBV drug resistance: mechanisms, detection and interpretation.
Shaw T, Bartholomeusz A, Locarnini S. Shaw T, et al. Among authors: locarnini s. J Hepatol. 2006 Mar;44(3):593-606. doi: 10.1016/j.jhep.2006.01.001. Epub 2006 Jan 19. J Hepatol. 2006. PMID: 16455151 Review. No abstract available.
Defective hepatitis B virus DNA is not associated with disease status but is reduced by polymerase mutations associated with drug resistance.
Preiss S, Littlejohn M, Angus P, Thompson A, Desmond P, Lewin SR, Sasadeusz J, Matthews G, Dore GJ, Shaw T, Sozzi V, Yuen L, Lau G, Ayres A, Thio C, Avihingsanon A, Ruxrungtham K, Locarnini S, Revill PA. Preiss S, et al. Among authors: locarnini s. Hepatology. 2008 Sep;48(3):741-9. doi: 10.1002/hep.22386. Hepatology. 2008. PMID: 18571815 Free PMC article.
390 results