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A phase 1, single centre, open label, escalating dose study to assess the safety, tolerability and immunogenicity of a therapeutic human papillomavirus (HPV) DNA vaccine (AMV002) for HPV-associated head and neck cancer (HNC).
Chandra J, Woo WP, Finlayson N, Liu HY, McGrath M, Ladwa R, Brauer M, Xu Y, Hanson S, Panizza B, Frazer IH, Porceddu SV. Chandra J, et al. Among authors: xu y. Cancer Immunol Immunother. 2021 Mar;70(3):743-753. doi: 10.1007/s00262-020-02720-7. Epub 2020 Sep 12. Cancer Immunol Immunother. 2021. PMID: 32918586 Free PMC article. Clinical Trial.
Different patterns of immune responses but similar control of a simian-human immunodeficiency virus 89.6P mucosal challenge by modified vaccinia virus Ankara (MVA) and DNA/MVA vaccines.
Amara RR, Villinger F, Staprans SI, Altman JD, Montefiori DC, Kozyr NL, Xu Y, Wyatt LS, Earl PL, Herndon JG, McClure HM, Moss B, Robinson HL. Amara RR, et al. Among authors: xu y. J Virol. 2002 Aug;76(15):7625-31. doi: 10.1128/jvi.76.15.7625-7631.2002. J Virol. 2002. PMID: 12097576 Free PMC article.
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