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Low-dose total body irradiation (TBI) and fludarabine followed by hematopoietic cell transplantation (HCT) from HLA-matched or mismatched unrelated donors and postgrafting immunosuppression with cyclosporine and mycophenolate mofetil (MMF) can induce durable complete chimerism and sustained remissions in patients with hematological diseases.
Niederwieser D, Maris M, Shizuru JA, Petersdorf E, Hegenbart U, Sandmaier BM, Maloney DG, Storer B, Lange T, Chauncey T, Deininger M, Pönisch W, Anasetti C, Woolfrey A, Little MT, Blume KG, McSweeney PA, Storb RF. Niederwieser D, et al. Among authors: lange t. Blood. 2003 Feb 15;101(4):1620-9. doi: 10.1182/blood-2002-05-1340. Epub 2002 Oct 3. Blood. 2003. PMID: 12393457 Free article.
Treatment for acute myelogenous leukemia by low-dose, total-body, irradiation-based conditioning and hematopoietic cell transplantation from related and unrelated donors.
Hegenbart U, Niederwieser D, Sandmaier BM, Maris MB, Shizuru JA, Greinix H, Cordonnier C, Rio B, Gratwohl A, Lange T, Al-Ali H, Storer B, Maloney D, McSweeney P, Chauncey T, Agura E, Bruno B, Maziarz RT, Petersen F, Storb R. Hegenbart U, et al. Among authors: lange t. J Clin Oncol. 2006 Jan 20;24(3):444-53. doi: 10.1200/JCO.2005.03.1765. Epub 2005 Dec 12. J Clin Oncol. 2006. PMID: 16344316
Nonmyeloablative unrelated donor hematopoietic cell transplantation to treat patients with poor-risk, relapsed, or refractory multiple myeloma.
Georges GE, Maris MB, Maloney DG, Sandmaier BM, Sorror ML, Shizuru JA, Lange T, Agura ED, Bruno B, McSweeney PA, Pulsipher MA, Chauncey TR, Mielcarek M, Storer BE, Storb R. Georges GE, et al. Among authors: lange t. Biol Blood Marrow Transplant. 2007 Apr;13(4):423-32. doi: 10.1016/j.bbmt.2006.11.011. Epub 2007 Feb 1. Biol Blood Marrow Transplant. 2007. PMID: 17287157 Free PMC article. Clinical Trial.
Extended mycophenolate mofetil and shortened cyclosporine failed to reduce graft-versus-host disease after unrelated hematopoietic cell transplantation with nonmyeloablative conditioning.
Baron F, Sandmaier BM, Storer BE, Maris MB, Langston AA, Lange T, Petersdorf E, Bethge W, Maziarz RT, McSweeney PA, Pulsipher MA, Wade JC, Chauncey TR, Shizuru JA, Sorror ML, Woolfrey AE, Maloney DG, Storb R. Baron F, et al. Among authors: lange t. Biol Blood Marrow Transplant. 2007 Sep;13(9):1041-8. doi: 10.1016/j.bbmt.2007.05.011. Epub 2007 Jul 20. Biol Blood Marrow Transplant. 2007. PMID: 17697966 Free PMC article. Clinical Trial.
Reduced-intensity conditioning followed by allogeneic hematopoietic cell transplantation for adult patients with myelodysplastic syndrome and myeloproliferative disorders.
Laport GG, Sandmaier BM, Storer BE, Scott BL, Stuart MJ, Lange T, Maris MB, Agura ED, Chauncey TR, Wong RM, Forman SJ, Petersen FB, Wade JC, Epner E, Bruno B, Bethge WA, Curtin PT, Maloney DG, Blume KG, Storb RF. Laport GG, et al. Among authors: lange t. Biol Blood Marrow Transplant. 2008 Feb;14(2):246-55. doi: 10.1016/j.bbmt.2007.11.012. Biol Blood Marrow Transplant. 2008. PMID: 18215785 Free PMC article. Clinical Trial.
Long-term outcome of patients with multiple myeloma after autologous hematopoietic cell transplantation and nonmyeloablative allografting.
Rotta M, Storer BE, Sahebi F, Shizuru JA, Bruno B, Lange T, Agura ED, McSweeney PA, Pulsipher MA, Hari P, Maziarz RT, Chauncey TR, Appelbaum FR, Sorror ML, Bensinger W, Sandmaier BM, Storb RF, Maloney DG. Rotta M, et al. Among authors: lange t. Blood. 2009 Apr 2;113(14):3383-91. doi: 10.1182/blood-2008-07-170746. Epub 2008 Nov 17. Blood. 2009. PMID: 19015394 Free PMC article. Clinical Trial.
Salvage allogeneic hematopoietic cell transplantation with fludarabine and low-dose total body irradiation after rejection of first allografts.
Gyurkocza B, Cao TM, Storb RF, Lange T, Leisenring W, Franke GN, Sorror M, Hoppe R, Maloney DG, Negrin RS, Shizuru JA, Sandmaier BM. Gyurkocza B, et al. Among authors: lange t. Biol Blood Marrow Transplant. 2009 Oct;15(10):1314-22. doi: 10.1016/j.bbmt.2009.06.011. Epub 2009 Aug 3. Biol Blood Marrow Transplant. 2009. PMID: 19747640 Free PMC article.
1,448 results