Aaronson SA - Search Results

1

P53-mediated induction of Cox-2 counteracts p53- or genotoxic stress-induced apoptosis.

Han JA, Kim JI, Ongusaha PP, Hwang DH, Ballou LR, Mahale A, Aaronson SA, Lee SW. Han JA, et al. Among authors: aaronson sa. EMBO J. 2002 Nov 1;21(21):5635-44. doi: 10.1093/emboj/cdf591. EMBO J. 2002. PMID: 12411481 Free PMC article.

2

p53 induction and activation of DDR1 kinase counteract p53-mediated apoptosis and influence p53 regulation through a positive feedback loop.

Ongusaha PP, Kim JI, Fang L, Wong TW, Yancopoulos GD, Aaronson SA, Lee SW. Ongusaha PP, et al. Among authors: aaronson sa. EMBO J. 2003 Mar 17;22(6):1289-301. doi: 10.1093/emboj/cdg129. EMBO J. 2003. PMID: 12628922 Free PMC article.

3

Discoidin domain receptor 1 receptor tyrosine kinase induces cyclooxygenase-2 and promotes chemoresistance through nuclear factor-kappaB pathway activation.

Das S, Ongusaha PP, Yang YS, Park JM, Aaronson SA, Lee SW. Das S, et al. Among authors: aaronson sa. Cancer Res. 2006 Aug 15;66(16):8123-30. doi: 10.1158/0008-5472.CAN-06-1215. Cancer Res. 2006. PMID: 16912190

4

RhoE is a pro-survival p53 target gene that inhibits ROCK I-mediated apoptosis in response to genotoxic stress.

Ongusaha PP, Kim HG, Boswell SA, Ridley AJ, Der CJ, Dotto GP, Kim YB, Aaronson SA, Lee SW. Ongusaha PP, et al. Among authors: aaronson sa. Curr Biol. 2006 Dec 19;16(24):2466-72. doi: 10.1016/j.cub.2006.10.056. Curr Biol. 2006. Retraction in: Curr Biol. 2019 Jun 17;29(12):2107. doi: 10.1016/j.cub.2019.05.065. PMID: 17174923 Free PMC article. Retracted.

5

CDIP, a novel pro-apoptotic gene, regulates TNFalpha-mediated apoptosis in a p53-dependent manner.

Brown L, Ongusaha PP, Kim HG, Nuti S, Mandinova A, Lee JW, Khosravi-Far R, Aaronson SA, Lee SW. Brown L, et al. Among authors: aaronson sa. EMBO J. 2007 Jul 25;26(14):3410-22. doi: 10.1038/sj.emboj.7601779. Epub 2007 Jun 28. EMBO J. 2007. PMID: 17599062 Free PMC article.

6

GAMT, a p53-inducible modulator of apoptosis, is critical for the adaptive response to nutrient stress.

Ide T, Brown-Endres L, Chu K, Ongusaha PP, Ohtsuka T, El-Deiry WS, Aaronson SA, Lee SW. Ide T, et al. Among authors: aaronson sa. Mol Cell. 2009 Nov 13;36(3):379-92. doi: 10.1016/j.molcel.2009.09.031. Mol Cell. 2009. Retraction in: Mol Cell. 2013 Aug 22;51(4):552. doi: 10.1016/j.molcel.2013.08.005. PMID: 19917247 Free PMC article. Retracted.

7

p53 induction of heparin-binding EGF-like growth factor counteracts p53 growth suppression through activation of MAPK and PI3K/Akt signaling cascades.

Fang L, Li G, Liu G, Lee SW, Aaronson SA. Fang L, et al. Among authors: aaronson sa. EMBO J. 2001 Apr 17;20(8):1931-9. doi: 10.1093/emboj/20.8.1931. EMBO J. 2001. PMID: 11296226 Free PMC article.

8

Inhibition of p21-mediated ROS accumulation can rescue p21-induced senescence.

Macip S, Igarashi M, Fang L, Chen A, Pan ZQ, Lee SW, Aaronson SA. Macip S, et al. Among authors: aaronson sa. EMBO J. 2002 May 1;21(9):2180-8. doi: 10.1093/emboj/21.9.2180. EMBO J. 2002. PMID: 11980715 Free PMC article.

9

ASC is a Bax adaptor and regulates the p53-Bax mitochondrial apoptosis pathway.

Ohtsuka T, Ryu H, Minamishima YA, Macip S, Sagara J, Nakayama KI, Aaronson SA, Lee SW. Ohtsuka T, et al. Among authors: aaronson sa. Nat Cell Biol. 2004 Feb;6(2):121-8. doi: 10.1038/ncb1087. Epub 2004 Jan 18. Nat Cell Biol. 2004. PMID: 14730312

10

Hzf Determines cell survival upon genotoxic stress by modulating p53 transactivation.

Das S, Raj L, Zhao B, Kimura Y, Bernstein A, Aaronson SA, Lee SW. Das S, et al. Among authors: aaronson sa. Cell. 2007 Aug 24;130(4):624-37. doi: 10.1016/j.cell.2007.06.013. Cell. 2007. PMID: 17719541 Free PMC article.

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