Dewachter I - Search Results

1

Axonal transport, tau protein, and neurodegeneration in Alzheimer's disease.

Terwel D, Dewachter I, Van Leuven F. Terwel D, et al. Among authors: dewachter i. Neuromolecular Med. 2002;2(2):151-65. doi: 10.1385/NMM:2:2:151. Neuromolecular Med. 2002. PMID: 12428809 Review.

2

Basolateral secretion of amyloid precursor protein in Madin-Darby canine kidney cells is disturbed by alterations of intracellular pH and by introducing a mutation associated with familial Alzheimer's disease.

De Strooper B, Craessaerts K, Dewachter I, Moechars D, Greenberg B, Van Leuven F, Van den Berghe H. De Strooper B, et al. Among authors: dewachter i. J Biol Chem. 1995 Feb 24;270(8):4058-65. doi: 10.1074/jbc.270.8.4058. J Biol Chem. 1995. PMID: 7876155 Free article.

3

Expression in brain of amyloid precursor protein mutated in the alpha-secretase site causes disturbed behavior, neuronal degeneration and premature death in transgenic mice.

Moechars D, Lorent K, De Strooper B, Dewachter I, Van Leuven F. Moechars D, et al. Among authors: dewachter i. EMBO J. 1996 Mar 15;15(6):1265-74. EMBO J. 1996. PMID: 8635459 Free PMC article.

4

Transgenic mice expressing an alpha-secretion mutant of the amyloid precursor protein in the brain develop a progressive CNS disorder.

Moechars D, Lorent K, Dewachter I, Baekelandt V, De Strooper B, Van Leuven F. Moechars D, et al. Among authors: dewachter i. Behav Brain Res. 1998 Sep;95(1):55-64. doi: 10.1016/s0166-4328(97)00210-6. Behav Brain Res. 1998. PMID: 9754877

5

Early phenotypic changes in transgenic mice that overexpress different mutants of amyloid precursor protein in brain.

Moechars D, Dewachter I, Lorent K, Reversé D, Baekelandt V, Naidu A, Tesseur I, Spittaels K, Haute CV, Checler F, Godaux E, Cordell B, Van Leuven F. Moechars D, et al. Among authors: dewachter i. J Biol Chem. 1999 Mar 5;274(10):6483-92. doi: 10.1074/jbc.274.10.6483. J Biol Chem. 1999. PMID: 10037741 Free article.

6

Lipoprotein receptor-related protein in brain and in cultured neurons of mice deficient in receptor-associated protein and transgenic for apolipoprotein E4 or amyloid precursor protein.

Umans L, Serneels L, Lorent K, Dewachter I, Tesseur I, Moechars D, Van Leuven F. Umans L, et al. Among authors: dewachter i. Neuroscience. 1999;94(1):315-21. doi: 10.1016/s0306-4522(99)00242-0. Neuroscience. 1999. PMID: 10613521

7

Behavioral disturbances without amyloid deposits in mice overexpressing human amyloid precursor protein with Flemish (A692G) or Dutch (E693Q) mutation.

Kumar-Singh S, Dewachter I, Moechars D, Lübke U, De Jonghe C, Ceuterick C, Checler F, Naidu A, Cordell B, Cras P, Van Broeckhoven C, Van Leuven F. Kumar-Singh S, et al. Among authors: dewachter i. Neurobiol Dis. 2000 Feb;7(1):9-22. doi: 10.1006/nbdi.1999.0272. Neurobiol Dis. 2000. PMID: 10671319

8

Aging increased amyloid peptide and caused amyloid plaques in brain of old APP/V717I transgenic mice by a different mechanism than mutant presenilin1.

Dewachter I, Van Dorpe J, Smeijers L, Gilis M, Kuipéri C, Laenen I, Caluwaerts N, Moechars D, Checler F, Vanderstichele H, Van Leuven F. Dewachter I, et al. J Neurosci. 2000 Sep 1;20(17):6452-8. doi: 10.1523/JNEUROSCI.20-17-06452.2000. J Neurosci. 2000. PMID: 10964951 Free PMC article.

9

Prominent cerebral amyloid angiopathy in transgenic mice overexpressing the london mutant of human APP in neurons.

Van Dorpe J, Smeijers L, Dewachter I, Nuyens D, Spittaels K, Van Den Haute C, Mercken M, Moechars D, Laenen I, Kuiperi C, Bruynseels K, Tesseur I, Loos R, Vanderstichele H, Checler F, Sciot R, Van Leuven F. Van Dorpe J, et al. Among authors: dewachter i. Am J Pathol. 2000 Oct;157(4):1283-98. doi: 10.1016/S0002-9440(10)64644-5. Am J Pathol. 2000. PMID: 11021833 Free PMC article.

10

Modeling Alzheimer's disease in transgenic mice: effect of age and of presenilin1 on amyloid biochemistry and pathology in APP/London mice.

Dewachter I, van Dorpe J, Spittaels K, Tesseur I, Van Den Haute C, Moechars D, Van Leuven F. Dewachter I, et al. Exp Gerontol. 2000 Sep;35(6-7):831-41. doi: 10.1016/s0531-5565(00)00149-2. Exp Gerontol. 2000. PMID: 11053674 Review.

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