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A concise route to structurally diverse DMP 323 analogues via highly functionalized 1,4-diamines.
Org Lett. 2002 Dec 26;4(26):4673-6. doi: 10.1021/ol027074v.
Org Lett. 2002.
PMID: 12489958
Multivalent activation in temporary phosphate tethers: a new tether for small molecule synthesis.
Whitehead A, McReynolds MD, Moore JD, Hanson PR.
Whitehead A, et al. Among authors: mcreynolds md.
Org Lett. 2005 Jul 21;7(15):3375-8. doi: 10.1021/ol0512886.
Org Lett. 2005.
PMID: 16018664
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A temporary phosphorus tether/ring-closing metathesis strategy to functionalized 1,4-diamines.
Sprott KT, McReynolds MD, Hanson PR.
Sprott KT, et al. Among authors: mcreynolds md.
Org Lett. 2001 Nov 29;3(24):3939-42. doi: 10.1021/ol016828n.
Org Lett. 2001.
PMID: 11720574
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Synthesis of phosphorus and sulfur heterocycles via ring-closing olefin metathesis.
McReynolds MD, Dougherty JM, Hanson PR.
McReynolds MD, et al.
Chem Rev. 2004 May;104(5):2239-58. doi: 10.1021/cr020109k.
Chem Rev. 2004.
PMID: 15137790
Review.
No abstract available.
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(+)-saxitoxin: a first and second generation stereoselective synthesis.
Fleming JJ, McReynolds MD, Du Bois J.
Fleming JJ, et al. Among authors: mcreynolds md.
J Am Chem Soc. 2007 Aug 15;129(32):9964-75. doi: 10.1021/ja071501o. Epub 2007 Jul 21.
J Am Chem Soc. 2007.
PMID: 17658800
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Discovery of a Potent and Selective Sphingosine Kinase 1 Inhibitor through the Molecular Combination of Chemotype-Distinct Screening Hits.
Schnute ME, McReynolds MD, Carroll J, Chrencik J, Highkin MK, Iyanar K, Jerome G, Rains JW, Saabye M, Scholten JA, Yates M, Nagiec MM.
Schnute ME, et al. Among authors: mcreynolds md.
J Med Chem. 2017 Mar 23;60(6):2562-2572. doi: 10.1021/acs.jmedchem.7b00070. Epub 2017 Mar 6.
J Med Chem. 2017.
PMID: 28231433
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Modulation of cellular S1P levels with a novel, potent and specific inhibitor of sphingosine kinase-1.
Schnute ME, McReynolds MD, Kasten T, Yates M, Jerome G, Rains JW, Hall T, Chrencik J, Kraus M, Cronin CN, Saabye M, Highkin MK, Broadus R, Ogawa S, Cukyne K, Zawadzke LE, Peterkin V, Iyanar K, Scholten JA, Wendling J, Fujiwara H, Nemirovskiy O, Wittwer AJ, Nagiec MM.
Schnute ME, et al. Among authors: mcreynolds md.
Biochem J. 2012 May 15;444(1):79-88. doi: 10.1042/BJ20111929.
Biochem J. 2012.
PMID: 22397330
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