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Of mice and MEN1: Insulinomas in a conditional mouse knockout.
Crabtree JS, Scacheri PC, Ward JM, McNally SR, Swain GP, Montagna C, Hager JH, Hanahan D, Edlund H, Magnuson MA, Garrett-Beal L, Burns AL, Ried T, Chandrasekharappa SC, Marx SJ, Spiegel AM, Collins FS. Crabtree JS, et al. Among authors: spiegel am. Mol Cell Biol. 2003 Sep;23(17):6075-85. doi: 10.1128/MCB.23.17.6075-6085.2003. Mol Cell Biol. 2003. PMID: 12917331 Free PMC article.
Molecular pathology of the MEN1 gene.
Agarwal SK, Lee Burns A, Sukhodolets KE, Kennedy PA, Obungu VH, Hickman AB, Mullendore ME, Whitten I, Skarulis MC, Simonds WF, Mateo C, Crabtree JS, Scacheri PC, Ji Y, Novotny EA, Garrett-Beal L, Ward JM, Libutti SK, Richard Alexander H, Cerrato A, Parisi MJ, Santa Anna-A S, Oliver B, Chandrasekharappa SC, Collins FS, Spiegel AM, Marx SJ. Agarwal SK, et al. Among authors: spiegel am. Ann N Y Acad Sci. 2004 Apr;1014:189-98. doi: 10.1196/annals.1294.020. Ann N Y Acad Sci. 2004. PMID: 15153434 Review.
Genome-wide analysis of menin binding provides insights into MEN1 tumorigenesis.
Scacheri PC, Davis S, Odom DT, Crawford GE, Perkins S, Halawi MJ, Agarwal SK, Marx SJ, Spiegel AM, Meltzer PS, Collins FS. Scacheri PC, et al. Among authors: spiegel am. PLoS Genet. 2006 Apr;2(4):e51. doi: 10.1371/journal.pgen.0020051. Epub 2006 Apr 7. PLoS Genet. 2006. PMID: 16604156 Free PMC article.
Germline mutations of the MEN1 gene in familial multiple endocrine neoplasia type 1 and related states.
Agarwal SK, Kester MB, Debelenko LV, Heppner C, Emmert-Buck MR, Skarulis MC, Doppman JL, Kim YS, Lubensky IA, Zhuang Z, Green JS, Guru SC, Manickam P, Olufemi SE, Liotta LA, Chandrasekharappa SC, Collins FS, Spiegel AM, Burns AL, Marx SJ. Agarwal SK, et al. Among authors: spiegel am. Hum Mol Genet. 1997 Jul;6(7):1169-75. doi: 10.1093/hmg/6.7.1169. Hum Mol Genet. 1997. PMID: 9215689
Somatic mutation of the MEN1 gene in parathyroid tumours.
Heppner C, Kester MB, Agarwal SK, Debelenko LV, Emmert-Buck MR, Guru SC, Manickam P, Olufemi SE, Skarulis MC, Doppman JL, Alexander RH, Kim YS, Saggar SK, Lubensky IA, Zhuang Z, Liotta LA, Chandrasekharappa SC, Collins FS, Spiegel AM, Burns AL, Marx SJ. Heppner C, et al. Among authors: spiegel am. Nat Genet. 1997 Aug;16(4):375-8. doi: 10.1038/ng0897-375. Nat Genet. 1997. PMID: 9241276
Somatic mutations of the MEN1 tumor suppressor gene in sporadic gastrinomas and insulinomas.
Zhuang Z, Vortmeyer AO, Pack S, Huang S, Pham TA, Wang C, Park WS, Agarwal SK, Debelenko LV, Kester M, Guru SC, Manickam P, Olufemi SE, Yu F, Heppner C, Crabtree JS, Skarulis MC, Venzon DJ, Emmert-Buck MR, Spiegel AM, Chandrasekharappa SC, Collins FS, Burns AL, Marx SJ, Lubensky IA, et al. Zhuang Z, et al. Among authors: spiegel am. Cancer Res. 1997 Nov 1;57(21):4682-6. Cancer Res. 1997. PMID: 9354421
Identification of MEN1 gene mutations in sporadic carcinoid tumors of the lung.
Debelenko LV, Brambilla E, Agarwal SK, Swalwell JI, Kester MB, Lubensky IA, Zhuang Z, Guru SC, Manickam P, Olufemi SE, Chandrasekharappa SC, Crabtree JS, Kim YS, Heppner C, Burns AL, Spiegel AM, Marx SJ, Liotta LA, Collins FS, Travis WD, Emmert-Buck MR. Debelenko LV, et al. Among authors: spiegel am. Hum Mol Genet. 1997 Dec;6(13):2285-90. doi: 10.1093/hmg/6.13.2285. Hum Mol Genet. 1997. PMID: 9361035
372 results