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The practical synthesis of a uterine relaxant, bis(2-[[(2S)-2-([(2R)-2-hydroxy-2-[4-hydroxy-3-(2-hydroxyethyl)-phenyl]ethyl]amino)-1,2,3,4-tetrahydronaphthalen-7-yl]oxy]-N,N-dimethylacetamide) sulfate (KUR-1246).
Yanagi T, Kikuchi K, Takeuchi H, Ishikawa T, Nishimura T, Yamamoto I. Yanagi T, et al. Among authors: takeuchi h. Chem Pharm Bull (Tokyo). 2001 Aug;49(8):1018-23. doi: 10.1248/cpb.49.1018. Chem Pharm Bull (Tokyo). 2001. PMID: 11515570 Free article.
Orally active factor Xa inhibitors: investigation of a novel series of 3-amidinophenylsulfonamide derivatives using an amidoxime prodrug strategy.
Uchida M, Okazaki K, Mukaiyama H, Isawa H, Kobayashi H, Shiohara H, Muranaka H, Kai Y, Kikuchi N, Takeuchi H, Yokoyama K, Tsuji E, Ozawa T, Hoyano Y, Koizumi T, Misawa K, Hara K, Nakano S, Murakami Y, Okuno H. Uchida M, et al. Among authors: takeuchi h. Bioorg Med Chem Lett. 2008 Aug 15;18(16):4682-7. doi: 10.1016/j.bmcl.2008.07.009. Epub 2008 Jul 9. Bioorg Med Chem Lett. 2008. PMID: 18667303
Doublet chemotherapy, triplet chemotherapy, or doublet chemotherapy combined with radiotherapy as neoadjuvant treatment for locally advanced oesophageal cancer (JCOG1109 NExT): a randomised, controlled, open-label, phase 3 trial.
Kato K, Machida R, Ito Y, Daiko H, Ozawa S, Ogata T, Hara H, Kojima T, Abe T, Bamba T, Watanabe M, Kawakubo H, Shibuya Y, Tsubosa Y, Takegawa N, Kajiwara T, Baba H, Ueno M, Takeuchi H, Nakamura K, Kitagawa Y; JCOG1109 investigators. Kato K, et al. Among authors: takeuchi h. Lancet. 2024 Jun 11:S0140-6736(24)00745-1. doi: 10.1016/S0140-6736(24)00745-1. Online ahead of print. Lancet. 2024. PMID: 38876133
3,700 results