Nelson A - Search Results

1

Modifying the stereochemistry of an enzyme-catalyzed reaction by directed evolution.

Williams GJ, Domann S, Nelson A, Berry A. Williams GJ, et al. Among authors: nelson a. Proc Natl Acad Sci U S A. 2003 Mar 18;100(6):3143-8. doi: 10.1073/pnas.0635924100. Epub 2003 Mar 7. Proc Natl Acad Sci U S A. 2003. PMID: 12626743 Free PMC article.

2

Cloning, over-expression, purification, and characterisation of N-acetylneuraminate synthase from Streptococcus agalactiae.

Suryanti V, Nelson A, Berry A. Suryanti V, et al. Among authors: nelson a. Protein Expr Purif. 2003 Feb;27(2):346-56. doi: 10.1016/s1046-5928(02)00633-2. Protein Expr Purif. 2003. PMID: 12597896

3

Directed evolution of enzymes for biocatalysis and the life sciences.

Williams GJ, Nelson AS, Berry A. Williams GJ, et al. Among authors: nelson as. Cell Mol Life Sci. 2004 Dec;61(24):3034-46. doi: 10.1007/s00018-004-4234-5. Cell Mol Life Sci. 2004. PMID: 15583865 Review.

4

Creation of a tailored aldolase for the parallel synthesis of sialic acid mimetics.

Woodhall T, Williams G, Berry A, Nelson A. Woodhall T, et al. Among authors: nelson a. Angew Chem Int Ed Engl. 2005 Mar 29;44(14):2109-12. doi: 10.1002/anie.200462733. Angew Chem Int Ed Engl. 2005. PMID: 15742315 No abstract available.

5

Synthesis of screening substrates for the directed evolution of sialic acid aldolase: towards tailored enzymes for the preparation of influenza A sialidase inhibitor analogues.

Woodhall T, Williams G, Berry A, Nelson A. Woodhall T, et al. Among authors: nelson a. Org Biomol Chem. 2005 May 7;3(9):1795-800. doi: 10.1039/b501503k. Epub 2005 Apr 12. Org Biomol Chem. 2005. PMID: 15858666

6

Structure-guided saturation mutagenesis of N-acetylneuraminic acid lyase for the synthesis of sialic acid mimetics.

Williams GJ, Woodhall T, Nelson A, Berry A. Williams GJ, et al. Among authors: nelson a. Protein Eng Des Sel. 2005 May;18(5):239-46. doi: 10.1093/protein/gzi027. Epub 2005 May 16. Protein Eng Des Sel. 2005. PMID: 15897188

7

Creation of a pair of stereochemically complementary biocatalysts.

Williams GJ, Woodhall T, Farnsworth LM, Nelson A, Berry A. Williams GJ, et al. Among authors: nelson a. J Am Chem Soc. 2006 Dec 20;128(50):16238-47. doi: 10.1021/ja065233q. J Am Chem Soc. 2006. PMID: 17165777

8

Directed evolution of aldolases for exploitation in synthetic organic chemistry.

Bolt A, Berry A, Nelson A. Bolt A, et al. Among authors: nelson a. Arch Biochem Biophys. 2008 Jun 15;474(2):318-30. doi: 10.1016/j.abb.2008.01.005. Epub 2008 Jan 19. Arch Biochem Biophys. 2008. PMID: 18230325 Free PMC article. Review.

9

Structure of an Escherichia coli N-acetyl-D-neuraminic acid lyase mutant, E192N, in complex with pyruvate at 1.45 angstrom resolution.

Campeotto I, Carr SB, Trinh CH, Nelson AS, Berry A, Phillips SE, Pearson AR. Campeotto I, et al. Among authors: nelson as. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Nov 1;65(Pt 11):1088-90. doi: 10.1107/S1744309109037403. Epub 2009 Oct 24. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009. PMID: 19923724 Free PMC article.

10

Identification and characterization of important residues in the catalytic mechanism of CMP-Neu5Ac synthetase from Neisseria meningitidis.

Horsfall LE, Nelson A, Berry A. Horsfall LE, et al. Among authors: nelson a. FEBS J. 2010 Jul;277(13):2779-90. doi: 10.1111/j.1742-4658.2010.07696.x. Epub 2010 May 20. FEBS J. 2010. PMID: 20491913 Free PMC article.

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