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Binding of the positron emission tomography tracer Pittsburgh compound-B reflects the amount of amyloid-beta in Alzheimer's disease brain but not in transgenic mouse brain.
Klunk WE, Lopresti BJ, Ikonomovic MD, Lefterov IM, Koldamova RP, Abrahamson EE, Debnath ML, Holt DP, Huang GF, Shao L, DeKosky ST, Price JC, Mathis CA. Klunk WE, et al. Among authors: shao l. J Neurosci. 2005 Nov 16;25(46):10598-606. doi: 10.1523/JNEUROSCI.2990-05.2005. J Neurosci. 2005. PMID: 16291932 Free PMC article.
Anti-Amyloid Effects of Small Molecule Aβ-Binding Agents in PS1/APP Mice.
Cohen AD, Ikonomovic MD, Abrahamson EE, Paljug WR, Dekosky ST, Lefterov IM, Koldamova RP, Shao L, Debnath ML, Mason NS, Mathis CA, Klunk WE. Cohen AD, et al. Among authors: shao l. Lett Drug Des Discov. 2009 Sep;6(6):437. doi: 10.2174/157018009789057526. Lett Drug Des Discov. 2009. PMID: 20119496 Free PMC article.
Targeting prion amyloid deposits in vivo.
Sadowski M, Pankiewicz J, Scholtzova H, Tsai J, Li Y, Carp RI, Meeker HC, Gambetti P, Debnath M, Mathis CA, Shao L, Gan WB, Klunk WE, Wisniewski T. Sadowski M, et al. Among authors: shao l. J Neuropathol Exp Neurol. 2004 Jul;63(7):775-84. doi: 10.1093/jnen/63.7.775. J Neuropathol Exp Neurol. 2004. PMID: 15290902
An Abeta sequestration approach using non-antibody Abeta binding agents.
Matsuoka Y, Shao L, Debnath M, Lafrancois J, Becker A, Gray A, Aisen P, Mathis C, Klunk W, Duff K. Matsuoka Y, et al. Among authors: shao l. Curr Alzheimer Res. 2005 Apr;2(2):265-8. doi: 10.2174/1567205053585774. Curr Alzheimer Res. 2005. PMID: 15974928
4,219 results