Horwich AL - Search Results

1

Folding with and without encapsulation by cis- and trans-only GroEL-GroES complexes.

Farr GW, Fenton WA, Chaudhuri TK, Clare DK, Saibil HR, Horwich AL. Farr GW, et al. Among authors: horwich al. EMBO J. 2003 Jul 1;22(13):3220-30. doi: 10.1093/emboj/cdg313. EMBO J. 2003. PMID: 12839985 Free PMC article.

2

GroEL-GroES-mediated protein folding.

Horwich AL, Farr GW, Fenton WA. Horwich AL, et al. Chem Rev. 2006 May;106(5):1917-30. doi: 10.1021/cr040435v. Chem Rev. 2006. PMID: 16683761 Review. No abstract available.

3

Disulfide formation as a probe of folding in GroEL-GroES reveals correct formation of long-range bonds and editing of incorrect short-range ones.

Park ES, Fenton WA, Horwich AL. Park ES, et al. Among authors: horwich al. Proc Natl Acad Sci U S A. 2007 Feb 13;104(7):2145-50. doi: 10.1073/pnas.0610989104. Epub 2007 Feb 5. Proc Natl Acad Sci U S A. 2007. PMID: 17283341 Free PMC article.

4

Perturbed ATPase activity and not "close confinement" of substrate in the cis cavity affects rates of folding by tail-multiplied GroEL.

Farr GW, Fenton WA, Horwich AL. Farr GW, et al. Among authors: horwich al. Proc Natl Acad Sci U S A. 2007 Mar 27;104(13):5342-7. doi: 10.1073/pnas.0700820104. Epub 2007 Mar 19. Proc Natl Acad Sci U S A. 2007. PMID: 17372195 Free PMC article.

5

Two families of chaperonin: physiology and mechanism.

Horwich AL, Fenton WA, Chapman E, Farr GW. Horwich AL, et al. Annu Rev Cell Dev Biol. 2007;23:115-45. doi: 10.1146/annurev.cellbio.23.090506.123555. Annu Rev Cell Dev Biol. 2007. PMID: 17489689 Review.

6

The GroEL/GroES cis cavity as a passive anti-aggregation device.

Horwich AL, Apetri AC, Fenton WA. Horwich AL, et al. FEBS Lett. 2009 Aug 20;583(16):2654-62. doi: 10.1016/j.febslet.2009.06.049. Epub 2009 Jul 3. FEBS Lett. 2009. PMID: 19577567 Free PMC article. Review.

7

Chaperonin-mediated protein folding: using a central cavity to kinetically assist polypeptide chain folding.

Horwich AL, Fenton WA. Horwich AL, et al. Q Rev Biophys. 2009 May;42(2):83-116. doi: 10.1017/S0033583509004764. Epub 2009 Jul 29. Q Rev Biophys. 2009. PMID: 19638247 Review.

8

GroEL/GroES cycling: ATP binds to an open ring before substrate protein favoring protein binding and production of the native state.

Tyagi NK, Fenton WA, Horwich AL. Tyagi NK, et al. Among authors: horwich al. Proc Natl Acad Sci U S A. 2009 Dec 1;106(48):20264-9. doi: 10.1073/pnas.0911556106. Epub 2009 Nov 13. Proc Natl Acad Sci U S A. 2009. PMID: 19915138 Free PMC article.

9

ATP-triggered ADP release from the asymmetric chaperonin GroEL/GroES/ADP7 is not the rate-limiting step of the GroEL/GroES reaction cycle.

Tyagi NK, Fenton WA, Horwich AL. Tyagi NK, et al. Among authors: horwich al. FEBS Lett. 2010 Mar 5;584(5):951-3. doi: 10.1016/j.febslet.2010.01.021. Epub 2010 Jan 17. FEBS Lett. 2010. PMID: 20083109 Free PMC article.

10

Double mutant MBP refolds at same rate in free solution as inside the GroEL/GroES chaperonin chamber when aggregation in free solution is prevented.

Tyagi NK, Fenton WA, Deniz AA, Horwich AL. Tyagi NK, et al. Among authors: horwich al. FEBS Lett. 2011 Jun 23;585(12):1969-72. doi: 10.1016/j.febslet.2011.05.031. Epub 2011 May 20. FEBS Lett. 2011. PMID: 21609718 Free PMC article.

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