Joppa M - Search Results

1

Body weight regulation by selective MC4 receptor agonists and antagonists.

Foster AC, Joppa M, Markison S, Gogas KR, Fleck BA, Murphy BJ, Wolff M, Cismowski MJ, Ling N, Goodfellow VS, Chen C, Saunders J, Conlon PJ. Foster AC, et al. Among authors: joppa m. Ann N Y Acad Sci. 2003 Jun;994:103-10. doi: 10.1111/j.1749-6632.2003.tb03168.x. Ann N Y Acad Sci. 2003. PMID: 12851304 Review.

2

Central administration of peptide and small molecule MC4 receptor antagonists induce hyperphagia in mice and attenuate cytokine-induced anorexia.

Joppa MA, Ling N, Chen C, Gogas KR, Foster AC, Markison S. Joppa MA, et al. Peptides. 2005 Nov;26(11):2294-301. doi: 10.1016/j.peptides.2005.03.002. Epub 2005 Mar 25. Peptides. 2005. PMID: 16269355

3

Central infusion of the melanocortin receptor antagonist agouti-related peptide (AgRP(83-132)) prevents cachexia-related symptoms induced by radiation and colon-26 tumors in mice.

Joppa MA, Gogas KR, Foster AC, Markison S. Joppa MA, et al. Peptides. 2007 Mar;28(3):636-42. doi: 10.1016/j.peptides.2006.11.021. Epub 2007 Jan 3. Peptides. 2007. PMID: 17204351

4

Potent and orally active non-peptide antagonists of the human melanocortin-4 receptor based on a series of trans-2-disubstituted cyclohexylpiperazines.

Tucci FC, White NS, Markison S, Joppa M, Tran JA, Fleck BA, Madan A, Dyck BP, Parker J, Pontillo J, Arellano LM, Marinkovic D, Jiang W, Chen CW, Gogas KR, Goodfellow VS, Saunders J, Foster AC, Chen C. Tucci FC, et al. Among authors: joppa m. Bioorg Med Chem Lett. 2005 Oct 1;15(19):4389-95. doi: 10.1016/j.bmcl.2005.06.071. Bioorg Med Chem Lett. 2005. PMID: 16098742

5

A potent and selective nonpeptide antagonist of the melanocortin-4 receptor induces food intake in satiated mice.

Pontillo J, Tran JA, Markison S, Joppa M, Fleck BA, Marinkovic D, Arellano M, Tucci FC, Lanier M, Nelson J, Saunders J, Hoare SR, Foster AC, Chen C. Pontillo J, et al. Among authors: joppa m. Bioorg Med Chem Lett. 2005 May 16;15(10):2541-6. doi: 10.1016/j.bmcl.2005.03.053. Bioorg Med Chem Lett. 2005. PMID: 15863313

6

Discovery of 1-[2-[(1S)-(3-dimethylaminopropionyl)amino-2-methylpropyl]-4-methylphenyl]-4-[(2R)-methyl-3-(4-chlorophenyl)-propionyl]piperazine as an orally active antagonist of the melanocortin-4 receptor for the potential treatment of cachexia.

Chen C, Jiang W, Tucci F, Tran JA, Fleck BA, Hoare SR, Joppa M, Markison S, Wen J, Sai Y, Johns M, Madan A, Chen T, Chen CW, Marinkovic D, Arellano M, Saunders J, Foster AC. Chen C, et al. Among authors: joppa m. J Med Chem. 2007 Nov 1;50(22):5249-52. doi: 10.1021/jm070806a. Epub 2007 Oct 5. J Med Chem. 2007. PMID: 17918824

7

Role of corticotropin-releasing factor (CRF) receptors in the anorexic syndrome induced by CRF.

Pelleymounter MA, Joppa M, Carmouche M, Cullen MJ, Brown B, Murphy B, Grigoriadis DE, Ling N, Foster AC. Pelleymounter MA, et al. Among authors: joppa m. J Pharmacol Exp Ther. 2000 Jun;293(3):799-806. J Pharmacol Exp Ther. 2000. PMID: 10869378

8

Pharmacological evidence supporting a role for central corticotropin-releasing factor(2) receptors in behavioral, but not endocrine, response to environmental stress.

Pelleymounter MA, Joppa M, Ling N, Foster AC. Pelleymounter MA, et al. Among authors: joppa m. J Pharmacol Exp Ther. 2002 Jul;302(1):145-52. doi: 10.1124/jpet.302.1.145. J Pharmacol Exp Ther. 2002. PMID: 12065711

9

Behavioral and neuroendocrine effects of the selective CRF2 receptor agonists urocortin II and urocortin III.

Pelleymounter MA, Joppa M, Ling N, Foster AC. Pelleymounter MA, et al. Among authors: joppa m. Peptides. 2004 Apr;25(4):659-66. doi: 10.1016/j.peptides.2004.01.008. Peptides. 2004. PMID: 15165722

10

Selective stimulatory actions of corticotropin-releasing factor ligands on correlates of energy balance.

Heinrichs SC, Joppa M, Lapsansky J, Jeske K, Nelson R, De Souza E. Heinrichs SC, et al. Among authors: joppa m. Physiol Behav. 2001 Sep 1-15;74(1-2):5-13. doi: 10.1016/s0031-9384(01)00421-8. Physiol Behav. 2001. PMID: 11564446

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