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Vaccination with irradiated, autologous melanoma cells engineered to secrete granulocyte-macrophage colony-stimulating factor by adenoviral-mediated gene transfer augments antitumor immunity in patients with metastatic melanoma.
Soiffer R, Hodi FS, Haluska F, Jung K, Gillessen S, Singer S, Tanabe K, Duda R, Mentzer S, Jaklitsch M, Bueno R, Clift S, Hardy S, Neuberg D, Mulligan R, Webb I, Mihm M, Dranoff G. Soiffer R, et al. Among authors: dranoff g. J Clin Oncol. 2003 Sep 1;21(17):3343-50. doi: 10.1200/JCO.2003.07.005. J Clin Oncol. 2003. PMID: 12947071 Clinical Trial.
Gene transfer as cancer therapy.
Dranoff G, Mulligan RC. Dranoff G, et al. Adv Immunol. 1995;58:417-54. doi: 10.1016/s0065-2776(08)60624-0. Adv Immunol. 1995. PMID: 7741031 Review. No abstract available.
Phase I study of non-replicating autologous tumor cell injections using cells prepared with or without GM-CSF gene transduction in patients with metastatic renal cell carcinoma.
Berns AJ, Clift S, Cohen LK, Donehower RC, Dranoff G, Hauda KM, Jaffee EM, Lazenby AJ, Levitsky HI, Marshall FF, et al. Berns AJ, et al. Among authors: dranoff g. Hum Gene Ther. 1995 Mar;6(3):347-68. doi: 10.1089/hum.1995.6.3-347. Hum Gene Ther. 1995. PMID: 7779918 No abstract available.
Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity.
Dranoff G, Jaffee E, Lazenby A, Golumbek P, Levitsky H, Brose K, Jackson V, Hamada H, Pardoll D, Mulligan RC. Dranoff G, et al. Proc Natl Acad Sci U S A. 1993 Apr 15;90(8):3539-43. doi: 10.1073/pnas.90.8.3539. Proc Natl Acad Sci U S A. 1993. PMID: 8097319 Free PMC article.
221 results