Fischer JB - Search Results

1

McBurney RN, Daly D, Fischer JB, Hu LY, Subbarao K, Knapp AG, Kobayashi K, Margolin L, Reddy NL, Goldin SM. McBurney RN, et al. Among authors: fischer jb. J Neurotrauma. 1992 May;9 Suppl 2:S531-43. J Neurotrauma. 1992. PMID: 1319500 Review.

2

Neuroprotective use-dependent blockers of Na+ and Ca2+ channels controlling presynaptic release of glutamate.

Goldin SM, Subbarao K, Sharma R, Knapp AG, Fischer JB, Daly D, Durant GJ, Reddy NL, Hu LY, Magar S, et al. Goldin SM, et al. Among authors: fischer jb. Ann N Y Acad Sci. 1995 Sep 15;765:210-29. doi: 10.1111/j.1749-6632.1995.tb16578.x. Ann N Y Acad Sci. 1995. PMID: 7486608 Review.

3

In vitro neuroprotection by substituted guanidines with varying affinities for the N-methyl-D-aspartate receptor ionophore and for sigma sites.

Kirk CJ, Reddy NL, Fischer JB, Wolcott TC, Knapp AG, McBurney RN. Kirk CJ, et al. Among authors: fischer jb. J Pharmacol Exp Ther. 1994 Nov;271(2):1080-5. J Pharmacol Exp Ther. 1994. PMID: 7525936

4

Synthesis and structure-activity studies of N,N'-diarylguanidine derivatives. N-(1-naphthyl)-N'-(3-ethylphenyl)-N'-methylguanidine: a new, selective noncompetitive NMDA receptor antagonist.

Reddy NL, Hu LY, Cotter RE, Fischer JB, Wong WJ, McBurney RN, Weber E, Holmes DL, Wong ST, Prasad R, et al. Reddy NL, et al. Among authors: fischer jb. J Med Chem. 1994 Jan 21;37(2):260-7. doi: 10.1021/jm00028a009. J Med Chem. 1994. PMID: 8295213

5

Design, synthesis, and pharmacological evaluation of conformationally constrained analogues of N,N'-diaryl- and N-aryl-N-aralkylguanidines as potent inhibitors of neuronal Na+ channels.

Maillard MC, Perlman ME, Amitay O, Baxter D, Berlove D, Connaughton S, Fischer JB, Guo JQ, Hu LY, McBurney RN, Nagy PI, Subbarao K, Yost EA, Zhang L, Durant GJ. Maillard MC, et al. Among authors: fischer jb. J Med Chem. 1998 Jul 30;41(16):3048-61. doi: 10.1021/jm980124a. J Med Chem. 1998. PMID: 9685245

6

Identification and characterization of a potential ischemia-selective N-methyl-D-aspartate (NMDA) receptor ion-channel blocker, CNS 5788.

Padmanabhan S, Perlman ME, Zhang L, Moore D, Zhou D, Fischer JB, Durant GJ, McBurney RN. Padmanabhan S, et al. Among authors: fischer jb. Bioorg Med Chem Lett. 2001 Feb 26;11(4):501-4. doi: 10.1016/s0960-894x(00)00695-8. Bioorg Med Chem Lett. 2001. PMID: 11229757

7

Synthesis and pharmacological evaluation of N,N'-diarylguanidines as potent sodium channel blockers and anticonvulsant agents.

Reddy NL, Fan W, Magar SS, Perlman ME, Yost E, Zhang L, Berlove D, Fischer JB, Burke-Howie K, Wolcott T, Durant GJ. Reddy NL, et al. Among authors: fischer jb. J Med Chem. 1998 Aug 13;41(17):3298-302. doi: 10.1021/jm980134b. J Med Chem. 1998. PMID: 9703475

8

Synthesis and pharmacological evaluation of N-(2,5-disubstituted phenyl)-N'-(3-substituted phenyl)-N'-methylguanidines as N-methyl-D-aspartate receptor ion-channel blockers.

Hu LY, Guo J, Magar SS, Fischer JB, Burke-Howie KJ, Durant GJ. Hu LY, et al. Among authors: fischer jb. J Med Chem. 1997 Dec 19;40(26):4281-9. doi: 10.1021/jm970459c. J Med Chem. 1997. PMID: 9435897

9

Synthesis and characterization of a series of diarylguanidines that are noncompetitive N-methyl-D-aspartate receptor antagonists with neuroprotective properties.

Keana JF, McBurney RN, Scherz MW, Fischer JB, Hamilton PN, Smith SM, Server AC, Finkbeiner S, Stevens CF, Jahr C, et al. Keana JF, et al. Among authors: fischer jb. Proc Natl Acad Sci U S A. 1989 Jul;86(14):5631-5. doi: 10.1073/pnas.86.14.5631. Proc Natl Acad Sci U S A. 1989. PMID: 2546162 Free PMC article.

10

Solution-phase, parallel synthesis and pharmacological evaluation of acylguanidine derivatives as potential sodium channel blockers.

Padmanabhan S, Lavin RC, Thakker PM, Guo J, Zhang L, Moore D, Perlman ME, Kirk C, Daly D, Burke-Howie KJ, Wolcott T, Chari S, Berlove D, Fischer JB, Holt WF, Durant GJ, McBurney RN. Padmanabhan S, et al. Among authors: fischer jb. Bioorg Med Chem Lett. 2001 Dec 17;11(24):3151-5. doi: 10.1016/s0960-894x(01)00644-8. Bioorg Med Chem Lett. 2001. PMID: 11720863

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