Pitcher J - Search Results

1

Desensitization of the isolated beta 2-adrenergic receptor by beta-adrenergic receptor kinase, cAMP-dependent protein kinase, and protein kinase C occurs via distinct molecular mechanisms.

Pitcher J, Lohse MJ, Codina J, Caron MG, Lefkowitz RJ. Pitcher J, et al. Biochemistry. 1992 Mar 31;31(12):3193-7. doi: 10.1021/bi00127a021. Biochemistry. 1992. PMID: 1348186

2

Beta 2-adrenergic receptor stimulated, G protein-coupled receptor kinase 2 mediated, phosphorylation of ribosomal protein P2.

Freeman JL, Gonzalo P, Pitcher JA, Claing A, Lavergne JP, Reboud JP, Lefkowitz RJ. Freeman JL, et al. Among authors: pitcher ja. Biochemistry. 2002 Oct 22;41(42):12850-7. doi: 10.1021/bi020145d. Biochemistry. 2002. PMID: 12379128

3

G-protein-coupled receptors: regulatory role of receptor kinases and arrestin proteins.

Lefkowitz RJ, Inglese J, Koch WJ, Pitcher J, Attramadal H, Caron MG. Lefkowitz RJ, et al. Among authors: pitcher j. Cold Spring Harb Symp Quant Biol. 1992;57:127-33. doi: 10.1101/sqb.1992.057.01.016. Cold Spring Harb Symp Quant Biol. 1992. PMID: 1339651 Review. No abstract available.

4

Receptor-specific desensitization with purified proteins. Kinase dependence and receptor specificity of beta-arrestin and arrestin in the beta 2-adrenergic receptor and rhodopsin systems.

Lohse MJ, Andexinger S, Pitcher J, Trukawinski S, Codina J, Faure JP, Caron MG, Lefkowitz RJ. Lohse MJ, et al. Among authors: pitcher j. J Biol Chem. 1992 Apr 25;267(12):8558-64. J Biol Chem. 1992. PMID: 1349018 Free article.

5

Mechanisms of beta-adrenergic receptor desensitization and resensitization.

Lefkowitz RJ, Pitcher J, Krueger K, Daaka Y. Lefkowitz RJ, et al. Among authors: pitcher j. Adv Pharmacol. 1998;42:416-20. doi: 10.1016/s1054-3589(08)60777-2. Adv Pharmacol. 1998. PMID: 9327928 No abstract available.

6

Role of beta gamma subunits of G proteins in targeting the beta-adrenergic receptor kinase to membrane-bound receptors.

Pitcher JA, Inglese J, Higgins JB, Arriza JL, Casey PJ, Kim C, Benovic JL, Kwatra MM, Caron MG, Lefkowitz RJ. Pitcher JA, et al. Science. 1992 Aug 28;257(5074):1264-7. doi: 10.1126/science.1325672. Science. 1992. PMID: 1325672

7

Pleckstrin homology domain-mediated membrane association and activation of the beta-adrenergic receptor kinase requires coordinate interaction with G beta gamma subunits and lipid.

Pitcher JA, Touhara K, Payne ES, Lefkowitz RJ. Pitcher JA, et al. J Biol Chem. 1995 May 19;270(20):11707-10. doi: 10.1074/jbc.270.20.11707. J Biol Chem. 1995. PMID: 7744811 Free article.

8

Binding of G protein beta gamma-subunits to pleckstrin homology domains.

Touhara K, Inglese J, Pitcher JA, Shaw G, Lefkowitz RJ. Touhara K, et al. Among authors: pitcher ja. J Biol Chem. 1994 Apr 8;269(14):10217-20. J Biol Chem. 1994. PMID: 8144601 Free article.

9

Identification of the G protein-coupled receptor kinase phosphorylation sites in the human beta2-adrenergic receptor.

Fredericks ZL, Pitcher JA, Lefkowitz RJ. Fredericks ZL, et al. Among authors: pitcher ja. J Biol Chem. 1996 Jun 7;271(23):13796-803. doi: 10.1074/jbc.271.23.13796. J Biol Chem. 1996. PMID: 8662852 Free article.

10

Phosphatidylinositol 4,5-bisphosphate (PIP2)-enhanced G protein-coupled receptor kinase (GRK) activity. Location, structure, and regulation of the PIP2 binding site distinguishes the GRK subfamilies.

Pitcher JA, Fredericks ZL, Stone WC, Premont RT, Stoffel RH, Koch WJ, Lefkowitz RJ. Pitcher JA, et al. J Biol Chem. 1996 Oct 4;271(40):24907-13. doi: 10.1074/jbc.271.40.24907. J Biol Chem. 1996. PMID: 8798768 Free article.

We have shown previously that the membrane association of betaARK (beta-adrenergic receptor kinase) (GRK2) is mediated, in vitro, by the simultaneous binding of PIP2 and the betagamma subunits of heterotrimeric G proteins to the carboxyl-terminal pleckstrin homology domain of thi …

We have shown previously that the membrane association of betaARK (beta-adrenergic receptor kinase) (GRK2) is mediated, in vitro, by the sim …

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