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The chemopreventive agent N-(4-hydroxyphenyl)retinamide induces apoptosis through a mitochondrial pathway regulated by proteins from the Bcl-2 family.
Boya P, Morales MC, Gonzalez-Polo RA, Andreau K, Gourdier I, Perfettini JL, Larochette N, Deniaud A, Baran-Marszak F, Fagard R, Feuillard J, Asumendi A, Raphael M, Pau B, Brenner C, Kroemer G. Boya P, et al. Among authors: brenner c. Oncogene. 2003 Sep 18;22(40):6220-30. doi: 10.1038/sj.onc.1206827. Oncogene. 2003. PMID: 13679861
Potassium leakage during the apoptotic degradation phase.
Dallaporta B, Hirsch T, Susin SA, Zamzami N, Larochette N, Brenner C, Marzo I, Kroemer G. Dallaporta B, et al. Among authors: brenner c. J Immunol. 1998 Jun 1;160(11):5605-15. J Immunol. 1998. PMID: 9605166
Caspases disrupt mitochondrial membrane barrier function.
Marzo I, Susin SA, Petit PX, Ravagnan L, Brenner C, Larochette N, Zamzami N, Kroemer G. Marzo I, et al. Among authors: brenner c. FEBS Lett. 1998 May 8;427(2):198-202. doi: 10.1016/s0014-5793(98)00424-4. FEBS Lett. 1998. PMID: 9607311 Free article.
707 results