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Mirk/dyrk1B kinase destabilizes cyclin D1 by phosphorylation at threonine 288.
Zou Y, Ewton DZ, Deng X, Mercer SE, Friedman E. Zou Y, et al. J Biol Chem. 2004 Jun 25;279(26):27790-8. doi: 10.1074/jbc.M403042200. Epub 2004 Apr 9. J Biol Chem. 2004. PMID: 15075324 Free article.
Destabilization was confirmed by induction of a stable Mirk transfectant of Mv1Lu cells, which blocked cell migration (Zou, Y., Lim, S., Lee, K., Deng, X., and Friedman, E. (2003) J. ...
Destabilization was confirmed by induction of a stable Mirk transfectant of Mv1Lu cells, which blocked cell migration (Zou, Y. …
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