Keinänen TA - Search Results

1

Overexpression of spermidine/spermine N1-acetyltransferase elevates the threshold to pentylenetetrazol-induced seizure activity in transgenic mice.

Kaasinen SK, Gröhn OH, Keinänen TA, Alhonen L, Jänne J. Kaasinen SK, et al. Among authors: keinanen ta. Exp Neurol. 2003 Oct;183(2):645-52. doi: 10.1016/s0014-4886(03)00186-9. Exp Neurol. 2003. PMID: 14552906

2

Disturbed keratinocyte differentiation in transgenic mice and organotypic keratinocyte cultures as a result of spermidine/spermine N-acetyltransferase overexpression.

Pietilä M, Pirinen E, Keskitalo S, Juutinen S, Pasonen-Seppänen S, Keinänen T, Alhonen L, Jänne J. Pietilä M, et al. J Invest Dermatol. 2005 Mar;124(3):596-601. doi: 10.1111/j.0022-202X.2005.23636.x. J Invest Dermatol. 2005. PMID: 15737201 Free article.

3

Targeted disruption of spermidine/spermine N1-acetyltransferase gene in mouse embryonic stem cells. Effects on polyamine homeostasis and sensitivity to polyamine analogues.

Niiranen K, Pietilä M, Pirttilä TJ, Järvinen A, Halmekytö M, Korhonen VP, Keinänen TA, Alhonen L, Jänne J. Niiranen K, et al. Among authors: keinanen ta. J Biol Chem. 2002 Jul 12;277(28):25323-8. doi: 10.1074/jbc.M203599200. Epub 2002 May 8. J Biol Chem. 2002. PMID: 12000764 Free article.

4

Mice with targeted disruption of spermidine/spermine N1-acetyltransferase gene maintain nearly normal tissue polyamine homeostasis but show signs of insulin resistance upon aging.

Niiranen K, Keinänen TA, Pirinen E, Heikkinen S, Tusa M, Fatrai S, Suppola S, Pietilä M, Uimari A, Laakso M, Alhonen L, Jänne J. Niiranen K, et al. Among authors: keinanen ta. J Cell Mol Med. 2006 Oct-Dec;10(4):933-45. doi: 10.1111/j.1582-4934.2006.tb00536.x. J Cell Mol Med. 2006. PMID: 17125596 Free article.

5

Spermine analogue-regulated expression of spermidine/spermine N1-acetyltransferase and its effects on depletion of intracellular polyamine pools in mouse fetal fibroblasts.

Uimari A, Keinänen TA, Karppinen A, Woster P, Uimari P, Jänne J, Alhonen L. Uimari A, et al. Among authors: keinanen ta. Biochem J. 2009 Jul 29;422(1):101-9. doi: 10.1042/BJ20090411. Biochem J. 2009. PMID: 19473115 Free PMC article.

6

Concurrent overexpression of ornithine decarboxylase and spermidine/spermine N(1)-acetyltransferase further accelerates the catabolism of hepatic polyamines in transgenic mice.

Suppola S, Heikkinen S, Parkkinen JJ, Uusi-Oukari M, Korhonen VP, Keinänen T, Alhonen L, Jänne J. Suppola S, et al. Biochem J. 2001 Sep 1;358(Pt 2):343-8. doi: 10.1042/0264-6021:3580343. Biochem J. 2001. PMID: 11513732 Free PMC article.

7

Gossypol activates pancreatic polyamine catabolism in normal rats and induces acute pancreatitis in transgenic rats over-expressing spermidine/spermine N1-acetyltransferase.

Räsänen TL, Alhonen L, Sinervirta R, Uimari A, Kaasinen K, Keinänen T, Herzig KH, Jänne J. Räsänen TL, et al. Scand J Gastroenterol. 2003 Jul;38(7):787-93. doi: 10.1080/00365520310003273. Scand J Gastroenterol. 2003. PMID: 12889567

8

A polyamine analogue prevents acute pancreatitis and restores early liver regeneration in transgenic rats with activated polyamine catabolism.

Rasanen TL, Alhonen L, Sinervirta R, Keinanen T, Herzig KH, Suppola S, Khomutov AR, Vepsalainen J, Janne J. Rasanen TL, et al. J Biol Chem. 2002 Oct 18;277(42):39867-72. doi: 10.1074/jbc.M205967200. Epub 2002 Aug 13. J Biol Chem. 2002. PMID: 12181316 Free article.

9

Novel CoA-polyamine conjugates for effective inhibition of spermine/spermidine-N1-acetyltransferase.

Simonian A, Khomutov A, Hyvonen T, Grigorenko N, Keinanen T, Vepsalainen J, Alhonen L, Janne J. Simonian A, et al. Nucleosides Nucleotides Nucleic Acids. 2007;26(10-12):1245-8. doi: 10.1080/15257770701528214. Nucleosides Nucleotides Nucleic Acids. 2007. PMID: 18066761

10

Genetic approaches to the cellular functions of polyamines in mammals.

Jänne J, Alhonen L, Pietilä M, Keinänen TA. Jänne J, et al. Among authors: keinanen ta. Eur J Biochem. 2004 Mar;271(5):877-94. doi: 10.1111/j.1432-1033.2004.04009.x. Eur J Biochem. 2004. PMID: 15009201 Free article. Review.

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