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Large-scale animal model study uncovers altered brain pH and lactate levels as a transdiagnostic endophenotype of neuropsychiatric disorders involving cognitive impairment.
Hagihara H, Shoji H, Hattori S, Sala G, Takamiya Y, Tanaka M, Ihara M, Shibutani M, Hatada I, Hori K, Hoshino M, Nakao A, Mori Y, Okabe S, Matsushita M, Urbach A, Katayama Y, Matsumoto A, Nakayama KI, Katori S, Sato T, Iwasato T, Nakamura H, Goshima Y, Raveau M, Tatsukawa T, Yamakawa K, Takahashi N, Kasai H, Inazawa J, Nobuhisa I, Kagawa T, Taga T, Darwish M, Nishizono H, Takao K, Sapkota K, Nakazawa K, Takagi T, Fujisawa H, Sugimura Y, Yamanishi K, Rajagopal L, Hannah ND, Meltzer HY, Yamamoto T, Wakatsuki S, Araki T, Tabuchi K, Numakawa T, Kunugi H, Huang FL, Hayata-Takano A, Hashimoto H, Tamada K, Takumi T, Kasahara T, Kato T, Graef IA, Crabtree GR, Asaoka N, Hatakama H, Kaneko S, Kohno T, Hattori M, Hoshiba Y, Miyake R, Obi-Nagata K, Hayashi-Takagi A, Becker LJ, Yalcin I, Hagino Y, Kotajima-Murakami H, Moriya Y, Ikeda K, Kim H, Kaang BK, Otabi H, Yoshida Y, Toyoda A, Komiyama NH, Grant SGN, Ida-Eto M, Narita M, Matsumoto KI, Okuda-Ashitaka E, Ohmori I, Shimada T, Yamagata K, Ageta H, Tsuchida K, Inokuchi K, Sassa T, Kihara A, Fukasawa M, Usuda N, Katano T, Tanaka T, Yoshihara Y, Igarashi M, Hayashi T, Ishikawa K, Yamamoto S, Nishimura N, Nakada K, Hirotsune S, Egawa K, H… See abstract for full author list ➔ Hagihara H, et al. Among authors: meltzer hy. Elife. 2024 Mar 26;12:RP89376. doi: 10.7554/eLife.89376. Elife. 2024. PMID: 38529532 Free PMC article.
NU-1223, a simplified analog of alstonine, with 5-HT2cR agonist-like activity, rescues memory deficit and positive and negative symptoms in subchronic phencyclidine mouse model of schizophrenia.
Rajagopal L, Mahjour S, Huang M, Ryan CA, Elzokaky A, Csakai AJ, Orr MJ, Scheidt K, Meltzer HY. Rajagopal L, et al. Among authors: meltzer hy. Behav Brain Res. 2023 Oct 2;454:114614. doi: 10.1016/j.bbr.2023.114614. Epub 2023 Aug 10. Behav Brain Res. 2023. PMID: 37572758
Long-Term Outcome of Clozapine in Treatment-Resistant Schizophrenia.
Lee MA, Cola P, Jayathilake K, Meltzer HY. Lee MA, et al. Among authors: meltzer hy. J Clin Psychopharmacol. 2023 May-Jun 01;43(3):211-219. doi: 10.1097/JCP.0000000000001671. Epub 2023 Mar 28. J Clin Psychopharmacol. 2023. PMID: 36975722
Role of advanced glycation end products in the longitudinal association between muscular strength and psychotic symptoms among adolescents.
Suzuki K, Yamasaki S, Miyashita M, Ando S, Toriumi K, Yoshikawa A, Nakanishi M, Morimoto Y, Kanata S, Fujikawa S, Endo K, Koike S, Usami S, Itokawa M, Washizuka S, Hiraiwa-Hasegawa M, Meltzer HY, Kasai K, Nishida A, Arai M. Suzuki K, et al. Among authors: meltzer hy. Schizophrenia (Heidelb). 2022 Apr 27;8(1):44. doi: 10.1038/s41537-022-00249-5. Schizophrenia (Heidelb). 2022. PMID: 35853893 Free PMC article.
959 results