Thomas G - Search Results

1

The phosphorylation state of an autoregulatory domain controls PACS-1-directed protein traffic.

Scott GK, Gu F, Crump CM, Thomas L, Wan L, Xiang Y, Thomas G. Scott GK, et al. Among authors: thomas g, thomas l. EMBO J. 2003 Dec 1;22(23):6234-44. doi: 10.1093/emboj/cdg596. EMBO J. 2003. PMID: 14633983 Free PMC article.

2

Kex2-like endoproteases PC2 and PC3 accurately cleave a model prohormone in mammalian cells: evidence for a common core of neuroendocrine processing enzymes.

Thomas L, Leduc R, Thorne BA, Smeekens SP, Steiner DF, Thomas G. Thomas L, et al. Among authors: thomas g. Proc Natl Acad Sci U S A. 1991 Jun 15;88(12):5297-301. doi: 10.1073/pnas.88.12.5297. Proc Natl Acad Sci U S A. 1991. PMID: 1647029 Free PMC article.

3

Yeast KEX1 protease cleaves a prohormone processing intermediate in mammalian cells.

Thomas L, Cooper A, Bussey H, Thomas G. Thomas L, et al. Among authors: thomas g. J Biol Chem. 1990 Jul 5;265(19):10821-4. J Biol Chem. 1990. PMID: 2193026 Free article.

4

Human fur gene encodes a yeast KEX2-like endoprotease that cleaves pro-beta-NGF in vivo.

Bresnahan PA, Leduc R, Thomas L, Thorner J, Gibson HL, Brake AJ, Barr PJ, Thomas G. Bresnahan PA, et al. Among authors: thomas g, thomas l. J Cell Biol. 1990 Dec;111(6 Pt 2):2851-9. doi: 10.1083/jcb.111.6.2851. J Cell Biol. 1990. PMID: 2269657 Free PMC article.

5

Cell-type specific processing of neuroendocrine precursor proteins using vaccinia recombinants.

Thomas G, Thomas L, Thorne BA, Herbert E. Thomas G, et al. Among authors: thomas l. Biochimie. 1988 Jan;70(1):89-97. doi: 10.1016/0300-9084(88)90163-0. Biochimie. 1988. PMID: 3135846

6

Yeast KEX2 endopeptidase correctly cleaves a neuroendocrine prohormone in mammalian cells.

Thomas G, Thorne BA, Thomas L, Allen RG, Hruby DE, Fuller R, Thorner J. Thomas G, et al. Among authors: thomas l. Science. 1988 Jul 8;241(4862):226-30. doi: 10.1126/science.3291117. Science. 1988. PMID: 3291117

7

Intracellular trafficking and activation of the furin proprotein convertase: localization to the TGN and recycling from the cell surface.

Molloy SS, Thomas L, VanSlyke JK, Stenberg PE, Thomas G. Molloy SS, et al. Among authors: thomas g, thomas l. EMBO J. 1994 Jan 1;13(1):18-33. doi: 10.1002/j.1460-2075.1994.tb06231.x. EMBO J. 1994. PMID: 7508380 Free PMC article.

8

Inhibition of HIV-1 gp160-dependent membrane fusion by a furin-directed alpha 1-antitrypsin variant.

Anderson ED, Thomas L, Hayflick JS, Thomas G. Anderson ED, et al. Among authors: thomas g, thomas l. J Biol Chem. 1993 Nov 25;268(33):24887-91. J Biol Chem. 1993. PMID: 8227051 Free article.

Using site-directed mutagenesis, a variant alpha 1-antitrypsin (alpha 1-AT) was constructed which contains in its reactive site -Arg-X-X-Arg-, the minimal sequence required for efficient processing by furin (Molloy, S. S., Bresnahan, P. A., Leppla, S. H., Klimpel, K. R., and T …

Using site-directed mutagenesis, a variant alpha 1-antitrypsin (alpha 1-AT) was constructed which contains in its reactive site -Arg-X-X-Arg …

9

Intracellular trafficking of furin is modulated by the phosphorylation state of a casein kinase II site in its cytoplasmic tail.

Jones BG, Thomas L, Molloy SS, Thulin CD, Fry MD, Walsh KA, Thomas G. Jones BG, et al. Among authors: thomas g, thomas l. EMBO J. 1995 Dec 1;14(23):5869-83. doi: 10.1002/j.1460-2075.1995.tb00275.x. EMBO J. 1995. PMID: 8846780 Free PMC article.

10

Activation of the furin endoprotease is a multiple-step process: requirements for acidification and internal propeptide cleavage.

Anderson ED, VanSlyke JK, Thulin CD, Jean F, Thomas G. Anderson ED, et al. Among authors: thomas g. EMBO J. 1997 Apr 1;16(7):1508-18. doi: 10.1093/emboj/16.7.1508. EMBO J. 1997. PMID: 9130696 Free PMC article.

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