Yang Y - Search Results

1

Phenyl thiazolyl urea and carbamate derivatives as new inhibitors of bacterial cell-wall biosynthesis.

Francisco GD, Li Z, Albright JD, Eudy NH, Katz AH, Petersen PJ, Labthavikul P, Singh G, Yang Y, Rasmussen BA, Lin YI, Mansour TS. Francisco GD, et al. Among authors: yang y. Bioorg Med Chem Lett. 2004 Jan 5;14(1):235-8. doi: 10.1016/j.bmcl.2003.09.082. Bioorg Med Chem Lett. 2004. PMID: 14684334

2

Muraymycins, novel peptidoglycan biosynthesis inhibitors: semisynthesis and SAR of their derivatives.

Lin YI, Li Z, Francisco GD, McDonald LA, Davis RA, Singh G, Yang Y, Mansour TS. Lin YI, et al. Among authors: yang y. Bioorg Med Chem Lett. 2002 Sep 2;12(17):2341-4. doi: 10.1016/s0960-894x(02)00469-9. Bioorg Med Chem Lett. 2002. PMID: 12161129

3

2-Phenyl-5,6-dihydro-2H-thieno[3,2-c]pyrazol-3-ol derivatives as new inhibitors of bacterial cell wall biosynthesis.

Li Z, Francisco GD, Hu W, Labthavikul P, Petersen PJ, Severin A, Singh G, Yang Y, Rasmussen BA, Lin YI, Skotnicki JS, Mansour TS. Li Z, et al. Among authors: yang y. Bioorg Med Chem Lett. 2003 Aug 4;13(15):2591-4. doi: 10.1016/s0960-894x(03)00471-2. Bioorg Med Chem Lett. 2003. PMID: 12852973

4

Novel imidazole substituted 6-methylidene-penems as broad-spectrum beta-lactamase inhibitors.

Venkatesan AM, Agarwal A, Abe T, Ushirogochi H, Yamamura I, Kumagai T, Petersen PJ, Weiss WJ, Lenoy E, Yang Y, Shlaes DM, Ryan JL, Mansour TS. Venkatesan AM, et al. Among authors: yang y. Bioorg Med Chem. 2004 Nov 15;12(22):5807-17. doi: 10.1016/j.bmc.2004.08.039. Bioorg Med Chem. 2004. PMID: 15498657

5

4-Alkyl and 4,4'-dialkyl 1,2-bis(4-chlorophenyl)pyrazolidine-3,5-dione derivatives as new inhibitors of bacterial cell wall biosynthesis.

Kutterer KM, Davis JM, Singh G, Yang Y, Hu W, Severin A, Rasmussen BA, Krishnamurthy G, Failli A, Katz AH. Kutterer KM, et al. Among authors: yang y. Bioorg Med Chem Lett. 2005 May 16;15(10):2527-31. doi: 10.1016/j.bmcl.2005.03.058. Bioorg Med Chem Lett. 2005. PMID: 15863310

6

Pulvinones as bacterial cell wall biosynthesis inhibitors.

Antane S, Caufield CE, Hu W, Keeney D, Labthavikul P, Morris K, Naughton SM, Petersen PJ, Rasmussen BA, Singh G, Yang Y. Antane S, et al. Among authors: yang y. Bioorg Med Chem Lett. 2006 Jan 1;16(1):176-80. doi: 10.1016/j.bmcl.2005.09.021. Epub 2005 Oct 10. Bioorg Med Chem Lett. 2006. PMID: 16216496

7

3,5-dioxopyrazolidines, novel inhibitors of UDP-N- acetylenolpyruvylglucosamine reductase (MurB) with activity against gram-positive bacteria.

Yang Y, Severin A, Chopra R, Krishnamurthy G, Singh G, Hu W, Keeney D, Svenson K, Petersen PJ, Labthavikul P, Shlaes DM, Rasmussen BA, Failli AA, Shumsky JS, Kutterer KM, Gilbert A, Mansour TS. Yang Y, et al. Antimicrob Agents Chemother. 2006 Feb;50(2):556-64. doi: 10.1128/AAC.50.2.556-564.2006. Antimicrob Agents Chemother. 2006. PMID: 16436710 Free PMC article.

8

Structure-activity relationship of 6-methylidene penems bearing 6,5 bicyclic heterocycles as broad-spectrum beta-lactamase inhibitors: evidence for 1,4-thiazepine intermediates with C7 R stereochemistry by computational methods.

Venkatesan AM, Agarwal A, Abe T, Ushirogochi H, Yamamura I, Ado M, Tsuyoshi T, Dos Santos O, Gu Y, Sum FW, Li Z, Francisco G, Lin YI, Petersen PJ, Yang Y, Kumagai T, Weiss WJ, Shlaes DM, Knox JR, Mansour TS. Venkatesan AM, et al. Among authors: yang y. J Med Chem. 2006 Jul 27;49(15):4623-37. doi: 10.1021/jm060021p. J Med Chem. 2006. PMID: 16854068

9

Pyrazolidine-3,5-diones and 5-hydroxy-1H-pyrazol-3(2H)-ones, inhibitors of UDP-N-acetylenolpyruvyl glucosamine reductase.

Gilbert AM, Failli A, Shumsky J, Yang Y, Severin A, Singh G, Hu W, Keeney D, Petersen PJ, Katz AH. Gilbert AM, et al. Among authors: yang y. J Med Chem. 2006 Oct 5;49(20):6027-36. doi: 10.1021/jm060499t. J Med Chem. 2006. PMID: 17004716

10

5,5,6-Fused tricycles bearing imidazole and pyrazole 6-methylidene penems as broad-spectrum inhibitors of beta-lactamases.

Venkatesan AM, Agarwal A, Abe T, Ushirogochi H, Ado M, Tsuyoshi T, Dos Santos O, Li Z, Francisco G, Lin YI, Petersen PJ, Yang Y, Weiss WJ, Shlaes DM, Mansour TS. Venkatesan AM, et al. Among authors: yang y. Bioorg Med Chem. 2008 Feb 15;16(4):1890-902. doi: 10.1016/j.bmc.2007.11.006. Epub 2007 Nov 5. Bioorg Med Chem. 2008. PMID: 18061461

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