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Design of N-substituted peptomer ligands for EVH1 domains.
Zimmermann J, Kühne R, Volkmer-Engert R, Jarchau T, Walter U, Oschkinat H, Ball LJ. Zimmermann J, et al. Among authors: kuhne r. J Biol Chem. 2003 Sep 19;278(38):36810-8. doi: 10.1074/jbc.M305934200. Epub 2003 Jul 10. J Biol Chem. 2003. PMID: 12857736 Free article.
Solution structures of the YAP65 WW domain and the variant L30 K in complex with the peptides GTPPPPYTVG, N-(n-octyl)-GPPPY and PLPPY and the application of peptide libraries reveal a minimal binding epitope.
Pires JR, Taha-Nejad F, Toepert F, Ast T, Hoffmüller U, Schneider-Mergener J, Kühne R, Macias MJ, Oschkinat H. Pires JR, et al. Among authors: kuhne r. J Mol Biol. 2001 Dec 14;314(5):1147-56. doi: 10.1006/jmbi.2000.5199. J Mol Biol. 2001. PMID: 11743730
Addressing protein-protein interactions with small molecules: a Pro-Pro dipeptide mimic with a PPII helix conformation as a module for the synthesis of PRD-binding ligands.
Zaminer J, Brockmann C, Huy P, Opitz R, Reuter C, Beyermann M, Freund C, Müller M, Oschkinat H, Kühne R, Schmalz HG. Zaminer J, et al. Among authors: kuhne r. Angew Chem Int Ed Engl. 2010 Sep 17;49(39):7111-5. doi: 10.1002/anie.201001739. Angew Chem Int Ed Engl. 2010. PMID: 20803590 No abstract available.
127 results