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Mitochondrial aspartate aminotransferase 27/32-410. Partially active enzyme derivative produced by limited proteolytic cleavage of native enzyme.
Sandmeier E, Christen P. Sandmeier E, et al. Among authors: christen p. J Biol Chem. 1980 Nov 10;255(21):10284-9. J Biol Chem. 1980. PMID: 7430125 Free article.
., Ford, G. C., Glor, M., Jansonius, J. N., Mavrides, C., and Christen, P. (1979) J. Mol. Biol. 133, 161-180). The peptide bonds cleaved by trypsin are situated in the following stretch of the polypeptide chain which runs in exposed position on the surface of the su …
., Ford, G. C., Glor, M., Jansonius, J. N., Mavrides, C., and Christen, P. (1979) J. Mol. Biol. 133, 161-180). The peptide bon …
Stereospecific labilization of the C-4' pro-S hydrogen of pyridoxamine 5'-phosphate in aspartate aminotransferase. Activators and inhibitors.
Tobler HP, Gehring H, Christen P. Tobler HP, et al. Among authors: christen p. J Biol Chem. 1987 Jul 5;262(19):8985-9. J Biol Chem. 1987. PMID: 2885326 Free article.
Measurement of the stereospecific release of the pro-S proton from C-4' of enzyme-bound pyridoxamine 5'-phosphate provides an experimental means to probe parts of the active site of aspartate aminotransferase independently of substrate turnover (Tobler, H. P., Christen …
Measurement of the stereospecific release of the pro-S proton from C-4' of enzyme-bound pyridoxamine 5'-phosphate provides an experimental m …
Conformational changes in aspartate aminotransferase. Effect of active site ligands on peptide hydrogen-deuterium exchange.
Pfister K, Sandmeier E, Berchtold W, Christen P. Pfister K, et al. Among authors: christen p. J Biol Chem. 1985 Sep 25;260(21):11414-21. J Biol Chem. 1985. PMID: 4044562 Free article.
Binding of the coenzyme to the apoenzyme results in a marked retardation of hydrogen exchange; binding of the competitive inhibitor maleate to the pyridoxal enzyme induces a retardation of exchange somewhat exceeding that observed in the presence of the transaminating substrate p …
Binding of the coenzyme to the apoenzyme results in a marked retardation of hydrogen exchange; binding of the competitive inhibitor maleate …
362 results