Wittinghofer A - Search Results

1

Purification, crystallization and preliminary structural characterization of human Rap1GAP.

Daumke O, Wittinghofer A, Weyand M. Daumke O, et al. Among authors: wittinghofer a. Acta Crystallogr D Biol Crystallogr. 2004 Apr;60(Pt 4):752-4. doi: 10.1107/S0907444904002392. Epub 2004 Mar 23. Acta Crystallogr D Biol Crystallogr. 2004. PMID: 15039575

2

The GTPase-activating protein Rap1GAP uses a catalytic asparagine.

Daumke O, Weyand M, Chakrabarti PP, Vetter IR, Wittinghofer A. Daumke O, et al. Among authors: wittinghofer a. Nature. 2004 May 13;429(6988):197-201. doi: 10.1038/nature02505. Nature. 2004. PMID: 15141215

3

The purification and crystallization of mDia1 in complex with RhoC.

Rose R, Wittinghofer A, Weyand M. Rose R, et al. Among authors: wittinghofer a. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005 Feb 1;61(Pt 2):225-7. doi: 10.1107/S1744309105001065. Epub 2005 Feb 1. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005. PMID: 16511001 Free PMC article.

4

Purification and crystallization of the catalytic PRONE domain of RopGEF8 and its complex with Rop4 from Arabidopsis thaliana.

Thomas C, Weyand M, Wittinghofer A, Berken A. Thomas C, et al. Among authors: wittinghofer a. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Jun 1;62(Pt 6):607-10. doi: 10.1107/S1744309106018689. Epub 2006 May 31. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006. PMID: 16754995 Free PMC article.

5

Rap-specific GTPase activating protein follows an alternative mechanism.

Brinkmann T, Daumke O, Herbrand U, Kühlmann D, Stege P, Ahmadian MR, Wittinghofer A. Brinkmann T, et al. Among authors: wittinghofer a. J Biol Chem. 2002 Apr 12;277(15):12525-31. doi: 10.1074/jbc.M109176200. Epub 2002 Jan 25. J Biol Chem. 2002. PMID: 11812780 Free article.

6

Insight into catalysis of a unique GTPase reaction by a combined biochemical and FTIR approach.

Chakrabarti PP, Daumke O, Suveyzdis Y, Kötting C, Gerwert K, Wittinghofer A. Chakrabarti PP, et al. Among authors: wittinghofer a. J Mol Biol. 2007 Apr 6;367(4):983-95. doi: 10.1016/j.jmb.2006.11.022. Epub 2006 Nov 10. J Mol Biol. 2007. PMID: 17300802

7

Structural insight into filament formation by mammalian septins.

Sirajuddin M, Farkasovsky M, Hauer F, Kühlmann D, Macara IG, Weyand M, Stark H, Wittinghofer A. Sirajuddin M, et al. Among authors: wittinghofer a. Nature. 2007 Sep 20;449(7160):311-5. doi: 10.1038/nature06052. Epub 2007 Jul 18. Nature. 2007. PMID: 17637674

8

Synthesis of GTP-derived Ras ligands.

Soulère L, Aldrich C, Daumke O, Gail R, Kissau L, Wittinghofer A, Waldmann H. Soulère L, et al. Among authors: wittinghofer a. Chembiochem. 2004 Oct 4;5(10):1448-53. doi: 10.1002/cbic.200400133. Chembiochem. 2004. PMID: 15457534

9

Phosphorylation-independent interaction between 14-3-3 and exoenzyme S: from structure to pathogenesis.

Ottmann C, Yasmin L, Weyand M, Veesenmeyer JL, Diaz MH, Palmer RH, Francis MS, Hauser AR, Wittinghofer A, Hallberg B. Ottmann C, et al. Among authors: wittinghofer a. EMBO J. 2007 Feb 7;26(3):902-13. doi: 10.1038/sj.emboj.7601530. Epub 2007 Jan 18. EMBO J. 2007. PMID: 17235285 Free PMC article.

10

Structure of the Roc-COR domain tandem of C. tepidum, a prokaryotic homologue of the human LRRK2 Parkinson kinase.

Gotthardt K, Weyand M, Kortholt A, Van Haastert PJ, Wittinghofer A. Gotthardt K, et al. Among authors: wittinghofer a. EMBO J. 2008 Aug 20;27(16):2239-49. doi: 10.1038/emboj.2008.150. Epub 2008 Jul 24. EMBO J. 2008. PMID: 18650931 Free PMC article.

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