Bessire A - Search Results

1

An analytical method for the analysis of tulathromycin, an equilibrating triamilide, in bovine and porcine plasma and lung.

Gáler D, Hessong S, Beato B, Risk J, Inskeep P, Weerasinghe C, Schneider RP, Langer C, LaPerle J, Renouf D, Bessire A, Español E, Rafka R, Ragan C, Boettner W, Murphy T, Keller D, Benchaoui H, Nowakowski MA. Gáler D, et al. Among authors: bessire a. J Agric Food Chem. 2004 Apr 21;52(8):2179-91. doi: 10.1021/jf0351624. J Agric Food Chem. 2004. PMID: 15080618

2

A tag-free collisionally induced fragmentation approach to detect drug-adducted proteins by mass spectrometry.

Ballard TE, Dahal UP, Bessire AJ, Schneider RP, Geoghegan KF, Vaz AD. Ballard TE, et al. Among authors: bessire aj. Rapid Commun Mass Spectrom. 2015 Nov 30;29(22):2175-83. doi: 10.1002/rcm.7375. Rapid Commun Mass Spectrom. 2015. PMID: 26467230

3

The use of 18O-exchange and base-catalyzed N-dealkylation with liquid chromatography/tandem mass spectrometry to identify carbinolamide metabolites.

Bessire AJ, Vaz AD, Walker GS, Wang WW, Sharma R. Bessire AJ, et al. Rapid Commun Mass Spectrom. 2010 Jul 30;24(14):2151-61. doi: 10.1002/rcm.4595. Rapid Commun Mass Spectrom. 2010. PMID: 20552706

4

LC/MS Methods for Studying Lysosomal ADC Catabolism.

Bessire AJ, Subramanyam C. Bessire AJ, et al. Methods Mol Biol. 2020;2078:341-351. doi: 10.1007/978-1-4939-9929-3_24. Methods Mol Biol. 2020. PMID: 31643069

5

Determination of Antibody-Drug Conjugate Released Payload Species Using Directed in Vitro Assays and Mass Spectrometric Interrogation.

Bessire AJ, Ballard TE, Charati M, Cohen J, Green M, Lam MH, Loganzo F, Nolting B, Pierce B, Puthenveetil S, Roberts L, Schildknegt K, Subramanyam C. Bessire AJ, et al. Bioconjug Chem. 2016 Jul 20;27(7):1645-54. doi: 10.1021/acs.bioconjchem.6b00192. Epub 2016 Jun 13. Bioconjug Chem. 2016. PMID: 27206324

6

Deconstruction of activity-dependent covalent modification of heme in human neutrophil myeloperoxidase by multistage mass spectrometry (MS(4)).

Geoghegan KF, Varghese AH, Feng X, Bessire AJ, Conboy JJ, Ruggeri RB, Ahn K, Spath SN, Filippov SV, Conrad SJ, Carpino PA, Guimarães CR, Vajdos FF. Geoghegan KF, et al. Among authors: bessire aj. Biochemistry. 2012 Mar 13;51(10):2065-77. doi: 10.1021/bi201872j. Epub 2012 Mar 1. Biochemistry. 2012. PMID: 22352991

7

A rapid and specific derivatization procedure to identify acyl-glucuronides by mass spectrometry.

Vaz AD, Wang WW, Bessire AJ, Sharma R, Hagen AE. Vaz AD, et al. Rapid Commun Mass Spectrom. 2010 Jul 30;24(14):2109-21. doi: 10.1002/rcm.4621. Rapid Commun Mass Spectrom. 2010. PMID: 20552710

8

Discovery of microsomal triglyceride transfer protein (MTP) inhibitors with potential for decreased active metabolite load compared to dirlotapide.

Robinson RP, Bartlett JA, Bertinato P, Bessire AJ, Cosgrove J, Foley PM, Manion TB, Minich ML, Ramos B, Reese MR, Schmahai TJ, Swick AG, Tess DA, Vaz A, Wolford A. Robinson RP, et al. Among authors: bessire aj. Bioorg Med Chem Lett. 2011 Jul 15;21(14):4150-4. doi: 10.1016/j.bmcl.2011.05.099. Epub 2011 Jun 2. Bioorg Med Chem Lett. 2011. PMID: 21684740

9

Use of high-resolution mass spectrometry to investigate a metabolite interference during liquid chromatography/tandem mass spectrometric quantification of a small molecule in toxicokinetic study samples.

Furlong M, Bessire A, Song W, Huntington C, Groeber E. Furlong M, et al. Among authors: bessire a. Rapid Commun Mass Spectrom. 2010 Jul 15;24(13):1902-10. doi: 10.1002/rcm.4587. Rapid Commun Mass Spectrom. 2010. PMID: 20533320

10

Dirlotapide as a model substrate to refine structure-based drug design strategies on CYP3A4-catalyzed metabolism.

Sun H, Bessire AJ, Vaz A. Sun H, et al. Among authors: bessire aj. Bioorg Med Chem Lett. 2012 Jan 1;22(1):371-6. doi: 10.1016/j.bmcl.2011.10.121. Epub 2011 Nov 6. Bioorg Med Chem Lett. 2012. PMID: 22094027

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