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Lipid rafts mediate the synaptic localization of alpha-synuclein.
Fortin DL, Troyer MD, Nakamura K, Kubo S, Anthony MD, Edwards RH. Fortin DL, et al. Among authors: kubo s. J Neurosci. 2004 Jul 28;24(30):6715-23. doi: 10.1523/JNEUROSCI.1594-04.2004. J Neurosci. 2004. PMID: 15282274 Free PMC article.
Leucine-rich repeat kinase 2 associates with lipid rafts.
Hatano T, Kubo S, Imai S, Maeda M, Ishikawa K, Mizuno Y, Hattori N. Hatano T, et al. Among authors: kubo s. Hum Mol Genet. 2007 Mar 15;16(6):678-90. doi: 10.1093/hmg/ddm013. Epub 2007 Mar 6. Hum Mol Genet. 2007. PMID: 17341485
DJ-1 associates with synaptic membranes.
Usami Y, Hatano T, Imai S, Kubo S, Sato S, Saiki S, Fujioka Y, Ohba Y, Sato F, Funayama M, Eguchi H, Shiba K, Ariga H, Shen J, Hattori N. Usami Y, et al. Among authors: kubo s. Neurobiol Dis. 2011 Sep;43(3):651-62. doi: 10.1016/j.nbd.2011.05.014. Epub 2011 May 30. Neurobiol Dis. 2011. PMID: 21645620
Arylsulfatase A, a genetic modifier of Parkinson's disease, is an α-synuclein chaperone.
Lee JS, Kanai K, Suzuki M, Kim WS, Yoo HS, Fu Y, Kim DK, Jung BC, Choi M, Oh KW, Li Y, Nakatani M, Nakazato T, Sekimoto S, Funayama M, Yoshino H, Kubo SI, Nishioka K, Sakai R, Ueyama M, Mochizuki H, Lee HJ, Sardi SP, Halliday GM, Nagai Y, Lee PH, Hattori N, Lee SJ. Lee JS, et al. Among authors: kubo si. Brain. 2019 Sep 1;142(9):2845-2859. doi: 10.1093/brain/awz205. Brain. 2019. PMID: 31312839
Phosphorylation of α-synuclein at T64 results in distinct oligomers and exerts toxicity in models of Parkinson's disease.
Matsui H, Ito S, Matsui H, Ito J, Gabdulkhaev R, Hirose M, Yamanaka T, Koyama A, Kato T, Tanaka M, Uemura N, Matsui N, Hirokawa S, Yoshihama M, Shimozawa A, Kubo SI, Iwasaki K, Hasegawa M, Takahashi R, Hirai K, Kakita A, Onodera O. Matsui H, et al. Among authors: kubo si. Proc Natl Acad Sci U S A. 2023 Jun 6;120(23):e2214652120. doi: 10.1073/pnas.2214652120. Epub 2023 May 30. Proc Natl Acad Sci U S A. 2023. PMID: 37252975 Free PMC article.
Parkinson's disease-associated iPLA2-VIA/PLA2G6 regulates neuronal functions and α-synuclein stability through membrane remodeling.
Mori A, Hatano T, Inoshita T, Shiba-Fukushima K, Koinuma T, Meng H, Kubo SI, Spratt S, Cui C, Yamashita C, Miki Y, Yamamoto K, Hirabayashi T, Murakami M, Takahashi Y, Shindou H, Nonaka T, Hasegawa M, Okuzumi A, Imai Y, Hattori N. Mori A, et al. Among authors: kubo si. Proc Natl Acad Sci U S A. 2019 Oct 8;116(41):20689-20699. doi: 10.1073/pnas.1902958116. Epub 2019 Sep 23. Proc Natl Acad Sci U S A. 2019. PMID: 31548400 Free PMC article.
Clinicogenetic study of mutations in LRRK2 exon 41 in Parkinson's disease patients from 18 countries.
Tomiyama H, Li Y, Funayama M, Hasegawa K, Yoshino H, Kubo S, Sato K, Hattori T, Lu CS, Inzelberg R, Djaldetti R, Melamed E, Amouri R, Gouider-Khouja N, Hentati F, Hatano Y, Wang M, Imamichi Y, Mizoguchi K, Miyajima H, Obata F, Toda T, Farrer MJ, Mizuno Y, Hattori N. Tomiyama H, et al. Among authors: kubo s. Mov Disord. 2006 Aug;21(8):1102-8. doi: 10.1002/mds.20886. Mov Disord. 2006. PMID: 16622854
2,276 results