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Brain-derived neurotrophic factor regulates the expression and synaptic delivery of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor subunits in hippocampal neurons.
Caldeira MV, Melo CV, Pereira DB, Carvalho R, Correia SS, Backos DS, Carvalho AL, Esteban JA, Duarte CB. Caldeira MV, et al. Among authors: backos ds. J Biol Chem. 2007 Apr 27;282(17):12619-28. doi: 10.1074/jbc.M700607200. Epub 2007 Mar 2. J Biol Chem. 2007. PMID: 17337442 Free article.
Deglutarylation of glutaryl-CoA dehydrogenase by deacylating enzyme SIRT5 promotes lysine oxidation in mice.
Bhatt DP, Mills CA, Anderson KA, Henriques BJ, Lucas TG, Francisco S, Liu J, Ilkayeva OR, Adams AE, Kulkarni SR, Backos DS, Major MB, Grimsrud PA, Gomes CM, Hirschey MD. Bhatt DP, et al. Among authors: backos ds. J Biol Chem. 2022 Apr;298(4):101723. doi: 10.1016/j.jbc.2022.101723. Epub 2022 Feb 12. J Biol Chem. 2022. PMID: 35157847 Free PMC article.
Allosteric inhibitors of the Eya2 phosphatase are selective and inhibit Eya2-mediated cell migration.
Krueger AB, Drasin DJ, Lea WA, Patrick AN, Patnaik S, Backos DS, Matheson CJ, Hu X, Barnaeva E, Holliday MJ, Blevins MA, Robin TP, Eisenmesser EZ, Ferrer M, Simeonov A, Southall N, Reigan P, Marugan J, Ford HL, Zhao R. Krueger AB, et al. Among authors: backos ds. J Biol Chem. 2014 Jun 6;289(23):16349-61. doi: 10.1074/jbc.M114.566729. Epub 2014 Apr 22. J Biol Chem. 2014. PMID: 24755226 Free PMC article.
Lysine glutarylation is a protein posttranslational modification regulated by SIRT5.
Tan M, Peng C, Anderson KA, Chhoy P, Xie Z, Dai L, Park J, Chen Y, Huang H, Zhang Y, Ro J, Wagner GR, Green MF, Madsen AS, Schmiesing J, Peterson BS, Xu G, Ilkayeva OR, Muehlbauer MJ, Braulke T, Mühlhausen C, Backos DS, Olsen CA, McGuire PJ, Pletcher SD, Lombard DB, Hirschey MD, Zhao Y. Tan M, et al. Among authors: backos ds. Cell Metab. 2014 Apr 1;19(4):605-17. doi: 10.1016/j.cmet.2014.03.014. Cell Metab. 2014. PMID: 24703693 Free PMC article.
67 results