Nodwell MB - Search Results

1

Hydrophobic vancomycin derivatives with improved ADME properties: discovery of telavancin (TD-6424).

Leadbetter MR, Adams SM, Bazzini B, Fatheree PR, Karr DE, Krause KM, Lam BM, Linsell MS, Nodwell MB, Pace JL, Quast K, Shaw JP, Soriano E, Trapp SG, Villena JD, Wu TX, Christensen BG, Judice JK. Leadbetter MR, et al. Among authors: nodwell mb. J Antibiot (Tokyo). 2004 May;57(5):326-36. doi: 10.7164/antibiotics.57.326. J Antibiot (Tokyo). 2004. PMID: 15303493 Free article.

2

Vancomycin disulfide derivatives as antibacterial agents.

Mu Y, Nodwell M, Pace JL, Shaw JP, Judice JK. Mu Y, et al. Bioorg Med Chem Lett. 2004 Feb 9;14(3):735-8. doi: 10.1016/j.bmcl.2003.11.040. Bioorg Med Chem Lett. 2004. PMID: 14741279

3

Multivalent drug design. Synthesis and in vitro analysis of an array of vancomycin dimers.

Griffin JH, Linsell MS, Nodwell MB, Chen Q, Pace JL, Quast KL, Krause KM, Farrington L, Wu TX, Higgins DL, Jenkins TE, Christensen BG, Judice JK. Griffin JH, et al. Among authors: nodwell mb. J Am Chem Soc. 2003 May 28;125(21):6517-31. doi: 10.1021/ja021273s. J Am Chem Soc. 2003. PMID: 12785792

4

Exploring the positional attachment of glycopeptide/beta-lactam heterodimers.

Long DD, Aggen JB, Chinn J, Choi SK, Christensen BG, Fatheree PR, Green D, Hegde SS, Judice JK, Kaniga K, Krause KM, Leadbetter M, Linsell MS, Marquess DG, Moran EJ, Nodwell MB, Pace JL, Trapp SG, Turner SD. Long DD, et al. Among authors: nodwell mb. J Antibiot (Tokyo). 2008 Oct;61(10):603-14. doi: 10.1038/ja.2008.80. J Antibiot (Tokyo). 2008. PMID: 19168974

5

Discovery of TD-4306, a long-acting β2-agonist for the treatment of asthma and COPD.

McKinnell RM, Klein U, Linsell MS, Moran EJ, Nodwell MB, Pfeiffer JW, Thomas GR, Yu C, Jacobsen JR. McKinnell RM, et al. Among authors: nodwell mb. Bioorg Med Chem Lett. 2014 Jul 1;24(13):2871-6. doi: 10.1016/j.bmcl.2014.04.095. Epub 2014 May 4. Bioorg Med Chem Lett. 2014. PMID: 24835980

6

Effective GTP-replacing FtsZ inhibitors and antibacterial mechanism of action.

Artola M, Ruiz-Avila LB, Vergoñós A, Huecas S, Araujo-Bazán L, Martín-Fontecha M, Vázquez-Villa H, Turrado C, Ramírez-Aportela E, Hoegl A, Nodwell M, Barasoain I, Chacón P, Sieber SA, Andreu JM, López-Rodríguez ML. Artola M, et al. ACS Chem Biol. 2015 Mar 20;10(3):834-43. doi: 10.1021/cb500974d. Epub 2014 Dec 30. ACS Chem Biol. 2015. PMID: 25486266

7

Synthetic analogues of the microtubule-stabilizing sponge alkaloid ceratamine A are more active than the natural product.

Nodwell M, Zimmerman C, Roberge M, Andersen RJ. Nodwell M, et al. J Med Chem. 2010 Nov 11;53(21):7843-51. doi: 10.1021/jm101012q. J Med Chem. 2010. PMID: 20945907

8

Rugulactone and its analogues exert antibacterial effects through multiple mechanisms including inhibition of thiamine biosynthesis.

Nodwell MB, Menz H, Kirsch SF, Sieber SA. Nodwell MB, et al. Chembiochem. 2012 Jul 9;13(10):1439-46. doi: 10.1002/cbic.201200265. Epub 2012 May 31. Chembiochem. 2012. PMID: 22653914

9

Evaluation of α-pyrones and pyrimidones as photoaffinity probes for affinity-based protein profiling.

Battenberg OA, Nodwell MB, Sieber SA. Battenberg OA, et al. Among authors: nodwell mb. J Org Chem. 2011 Aug 5;76(15):6075-87. doi: 10.1021/jo201281c. Epub 2011 Jul 14. J Org Chem. 2011. PMID: 21726094

10

A subfamily of bacterial ribokinases utilizes a hemithioacetal for pyridoxal phosphate salvage.

Nodwell MB, Koch MF, Alte F, Schneider S, Sieber SA. Nodwell MB, et al. J Am Chem Soc. 2014 Apr 2;136(13):4992-9. doi: 10.1021/ja411785r. Epub 2014 Mar 19. J Am Chem Soc. 2014. PMID: 24601602

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