Bloem LJ - Search Results

1

Transgenic mice with cardiac-specific over-expression of MLK7 have increased mortality when exposed to chronic beta-adrenergic stimulation.

Christe M, Jin N, Wang X, Gould KE, Iversen PW, Yu X, Lorenz JN, Kadambi V, Zuckerman SH, Bloem LJ. Christe M, et al. Among authors: bloem lj. J Mol Cell Cardiol. 2004 Sep;37(3):705-15. doi: 10.1016/j.yjmcc.2004.06.004. J Mol Cell Cardiol. 2004. PMID: 15350844

2

Effect of C-terminal truncations on MLK7 catalytic activity and JNK activation.

Yu X, Bloem LJ. Yu X, et al. Among authors: bloem lj. Biochem Biophys Res Commun. 2003 Oct 17;310(2):452-7. doi: 10.1016/j.bbrc.2003.09.075. Biochem Biophys Res Commun. 2003. PMID: 14521931

3

Protein kinase C betaII activation induces angiotensin converting enzyme expression in neonatal rat cardiomyocytes.

Zhang Y, Bloem LJ, Yu L, Estridge TB, Iversen PW, McDonald CE, Schrementi JP, Wang X, Vlahos CJ, Wang J. Zhang Y, et al. Among authors: bloem lj. Cardiovasc Res. 2003 Jan;57(1):139-46. doi: 10.1016/s0008-6363(02)00610-7. Cardiovasc Res. 2003. PMID: 12504823

4

Complete inhibition of anisomycin and UV radiation but not cytokine induced JNK and p38 activation by an aryl-substituted dihydropyrrolopyrazole quinoline and mixed lineage kinase 7 small interfering RNA.

Wang X, Mader MM, Toth JE, Yu X, Jin N, Campbell RM, Smallwood JK, Christe ME, Chatterjee A, Goodson T Jr, Vlahos CJ, Matter WF, Bloem LJ. Wang X, et al. Among authors: bloem lj. J Biol Chem. 2005 May 13;280(19):19298-305. doi: 10.1074/jbc.M413059200. Epub 2005 Feb 28. J Biol Chem. 2005. PMID: 15737997 Free article.

5

The fall in creatine levels and creatine kinase isozyme changes in the failing heart are reversible: complex post-transcriptional regulation of the components of the CK system.

Shen W, Spindler M, Higgins MA, Jin N, Gill RM, Bloem LJ, Ryan TP, Ingwall JS. Shen W, et al. Among authors: bloem lj. J Mol Cell Cardiol. 2005 Sep;39(3):537-44. doi: 10.1016/j.yjmcc.2005.05.003. J Mol Cell Cardiol. 2005. PMID: 15978613

6

Tissue distribution and functional expression of a cDNA encoding a novel mixed lineage kinase.

Bloem LJ, Pickard TR, Acton S, Donoghue M, Beavis RC, Knierman MD, Wang X. Bloem LJ, et al. J Mol Cell Cardiol. 2001 Sep;33(9):1739-50. doi: 10.1006/jmcc.2001.1437. J Mol Cell Cardiol. 2001. PMID: 11549352

7

Decreased p38 MAPK activity in end-stage failing human myocardium: p38 MAPK alpha is the predominant isoform expressed in human heart.

Lemke LE, Bloem LJ, Fouts R, Esterman M, Sandusky G, Vlahos CJ. Lemke LE, et al. Among authors: bloem lj. J Mol Cell Cardiol. 2001 Aug;33(8):1527-40. doi: 10.1006/jmcc.2001.1415. J Mol Cell Cardiol. 2001. PMID: 11448140

8

Role of PRL-3, a human muscle-specific tyrosine phosphatase, in angiotensin-II signaling.

Matter WF, Estridge T, Zhang C, Belagaje R, Stancato L, Dixon J, Johnson B, Bloem L, Pickard T, Donaghue M, Acton S, Jeyaseelan R, Kadambi V, Vlahos CJ. Matter WF, et al. Biochem Biophys Res Commun. 2001 May 25;283(5):1061-8. doi: 10.1006/bbrc.2001.4881. Biochem Biophys Res Commun. 2001. PMID: 11355880

9

Characterization of LY3023414, a Novel PI3K/mTOR Dual Inhibitor Eliciting Transient Target Modulation to Impede Tumor Growth.

Smith MC, Mader MM, Cook JA, Iversen P, Ajamie R, Perkins E, Bloem L, Yip YY, Barda DA, Waid PP, Zeckner DJ, Young DA, Sanchez-Felix M, Donoho GP, Wacheck V. Smith MC, et al. Mol Cancer Ther. 2016 Oct;15(10):2344-2356. doi: 10.1158/1535-7163.MCT-15-0996. Epub 2016 Jul 20. Mol Cancer Ther. 2016. PMID: 27439478

10

Discovery and characterization of LY2784544, a small-molecule tyrosine kinase inhibitor of JAK2V617F.

Ma L, Clayton JR, Walgren RA, Zhao B, Evans RJ, Smith MC, Heinz-Taheny KM, Kreklau EL, Bloem L, Pitou C, Shen W, Strelow JM, Halstead C, Rempala ME, Parthasarathy S, Gillig JR, Heinz LJ, Pei H, Wang Y, Stancato LF, Dowless MS, Iversen PW, Burkholder TP. Ma L, et al. Among authors: bloem l. Blood Cancer J. 2013 Apr 12;3(4):e109. doi: 10.1038/bcj.2013.6. Blood Cancer J. 2013. PMID: 23584399 Free PMC article.

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