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Structural basis for the adherence of Plasmodium falciparum-infected erythrocytes to chondroitin 4-sulfate and design of novel photoactivable reagents for the identification of parasite adhesive proteins.
Gowda AS, Madhunapantula SV, Achur RN, Valiyaveettil M, Bhavanandan VP, Gowda DC. Gowda AS, et al. Among authors: valiyaveettil m. J Biol Chem. 2007 Jan 12;282(2):916-28. doi: 10.1074/jbc.M604741200. Epub 2006 Nov 3. J Biol Chem. 2007. PMID: 17085451 Free article.
Chondroitin sulfate proteoglycan but not hyaluronic acid is the receptor for the adherence of Plasmodium falciparum-infected erythrocytes in human placenta, and infected red blood cell adherence up-regulates the receptor expression.
Muthusamy A, Achur RN, Valiyaveettil M, Botti JJ, Taylor DW, Leke RF, Gowda DC. Muthusamy A, et al. Among authors: valiyaveettil m. Am J Pathol. 2007 Jun;170(6):1989-2000. doi: 10.2353/ajpath.2007.061238. Am J Pathol. 2007. PMID: 17525266 Free PMC article.
Characterization of proteoglycans of human placenta and identification of unique chondroitin sulfate proteoglycans of the intervillous spaces that mediate the adherence of Plasmodium falciparum-infected erythrocytes to the placenta.
Achur RN, Valiyaveettil M, Alkhalil A, Ockenhouse CF, Gowda DC. Achur RN, et al. Among authors: valiyaveettil m. J Biol Chem. 2000 Dec 22;275(51):40344-56. doi: 10.1074/jbc.M006398200. J Biol Chem. 2000. PMID: 11005814 Free article.
The identification and characterization of these CSPGs provide a valuable tool for understanding the precise molecular interactions involved in placental IRBC adherence and for the development of therapeutic strategies for maternal malaria. In the accompanying paper (Alkhalil, A. …
The identification and characterization of these CSPGs provide a valuable tool for understanding the precise molecular interactions involved …
44 results