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Inhibition of human immunodeficiency virus type 1 replication in human cells by Debio-025, a novel cyclophilin binding agent.
Ptak RG, Gallay PA, Jochmans D, Halestrap AP, Ruegg UT, Pallansch LA, Bobardt MD, de Béthune MP, Neyts J, De Clercq E, Dumont JM, Scalfaro P, Besseghir K, Wenger RM, Rosenwirth B. Ptak RG, et al. Among authors: besseghir k. Antimicrob Agents Chemother. 2008 Apr;52(4):1302-17. doi: 10.1128/AAC.01324-07. Epub 2008 Jan 22. Antimicrob Agents Chemother. 2008. PMID: 18212100 Free PMC article.
Naturally occurring capsid substitutions render HIV-1 cyclophilin A independent in human cells and TRIM-cyclophilin-resistant in Owl monkey cells.
Chatterji U, Bobardt MD, Stanfield R, Ptak RG, Pallansch LA, Ward PA, Jones MJ, Stoddart CA, Scalfaro P, Dumont JM, Besseghir K, Rosenwirth B, Gallay PA. Chatterji U, et al. Among authors: besseghir k. J Biol Chem. 2005 Dec 2;280(48):40293-300. doi: 10.1074/jbc.M506314200. Epub 2005 Sep 30. J Biol Chem. 2005. PMID: 16199531 Free article.
Cyclosporine A delivery to the eye: a pharmaceutical challenge.
Lallemand F, Felt-Baeyens O, Besseghir K, Behar-Cohen F, Gurny R. Lallemand F, et al. Among authors: besseghir k. Eur J Pharm Biopharm. 2003 Nov;56(3):307-18. doi: 10.1016/s0939-6411(03)00138-3. Eur J Pharm Biopharm. 2003. PMID: 14602172 Review.
Conversion of cyclosporine A prodrugs in human tears vs rabbits tears.
Lallemand F, Felt-Baeyens O, Rudaz S, Hamel AR, Hubler F, Wenger R, Mutter M, Besseghir K, Gurny R. Lallemand F, et al. Among authors: besseghir k. Eur J Pharm Biopharm. 2005 Jan;59(1):51-6. doi: 10.1016/j.ejpb.2004.07.002. Eur J Pharm Biopharm. 2005. PMID: 15567301
Formation of peptide impurities in polyester matrices during implant manufacturing.
Rothen-Weinhold A, Oudry N, Schwach-Abdellaoui K, Frutiger-Hughes S, Hughes GJ, Jeannerat D, Burger U, Besseghir K, Gurny R. Rothen-Weinhold A, et al. Among authors: besseghir k. Eur J Pharm Biopharm. 2000 May;49(3):253-7. doi: 10.1016/s0939-6411(00)00066-7. Eur J Pharm Biopharm. 2000. PMID: 10799817
33 results