Woo LW - Search Results

1

Crystal structure of human carbonic anhydrase II at 1.95 A resolution in complex with 667-coumate, a novel anti-cancer agent.

Lloyd MD, Pederick RL, Natesh R, Woo LW, Purohit A, Reed MJ, Acharya KR, Potter BV. Lloyd MD, et al. Among authors: woo lw. Biochem J. 2005 Feb 1;385(Pt 3):715-20. doi: 10.1042/BJ20041037. Biochem J. 2005. PMID: 15453828 Free PMC article.

2

2-difluoromethyloestrone 3-O-sulphamate, a highly potent steroid sulphatase inhibitor.

Reed JE, Woo LW, Robinson JJ, Leblond B, Leese MP, Purohit A, Reed MJ, Potter BV. Reed JE, et al. Among authors: woo lw. Biochem Biophys Res Commun. 2004 Apr 23;317(1):169-75. doi: 10.1016/j.bbrc.2004.03.023. Biochem Biophys Res Commun. 2004. PMID: 15047163

3

First crystal structures of human carbonic anhydrase II in complex with dual aromatase-steroid sulfatase inhibitors.

Lloyd MD, Thiyagarajan N, Ho YT, Woo LW, Sutcliffe OB, Purohit A, Reed MJ, Acharya KR, Potter BV. Lloyd MD, et al. Among authors: woo lw. Biochemistry. 2005 May 10;44(18):6858-66. doi: 10.1021/bi047692e. Biochemistry. 2005. PMID: 15865431

4

Bicyclic derivatives of the potent dual aromatase-steroid sulfatase inhibitor 2-bromo-4-{[(4-cyanophenyl)(4h-1,2,4-triazol-4-yl)amino]methyl}phenylsulfamate: synthesis, SAR, crystal structure, and in vitro and in vivo activities.

Wood PM, Woo LW, Labrosse JR, Thomas MP, Mahon MF, Chander SK, Purohit A, Reed MJ, Potter BV. Wood PM, et al. Among authors: woo lw. ChemMedChem. 2010 Sep 3;5(9):1577-93. doi: 10.1002/cmdc.201000203. ChemMedChem. 2010. PMID: 20632362

5

D-ring modified estrone derivatives as novel potent inhibitors of steroid sulfatase.

Fischer DS, Woo LW, Mahon MF, Purohit A, Reed MJ, Potter BV. Fischer DS, et al. Among authors: woo lw. Bioorg Med Chem. 2003 Apr 17;11(8):1685-700. doi: 10.1016/s0968-0896(03)00042-7. Bioorg Med Chem. 2003. PMID: 12659755

6

Novel D-ring modified steroid derivatives as potent, non-estrogenic, steroid sulfatase inhibitors with in vivo activity.

Fischer DS, Chander SK, Woo LW, Fenton JC, Purohit A, Reed MJ, Potter BV. Fischer DS, et al. Among authors: woo lw. J Steroid Biochem Mol Biol. 2003 Feb;84(2-3):343-9. doi: 10.1016/s0960-0760(03)00048-7. J Steroid Biochem Mol Biol. 2003. PMID: 12711021

7

Inhibition of MCF-7 breast cancer cell proliferation and in vivo steroid sulphatase activity by 2-methoxyoestradiol-bis-sulphamate.

Raobaikady B, Purohit A, Chander SK, Woo LW, Leese MP, Potter BV, Reed MJ. Raobaikady B, et al. Among authors: woo lw. J Steroid Biochem Mol Biol. 2003 Feb;84(2-3):351-8. doi: 10.1016/s0960-0760(03)00049-9. J Steroid Biochem Mol Biol. 2003. PMID: 12711022

8

First dual aromatase-steroid sulfatase inhibitors.

Woo LW, Sutcliffe OB, Bubert C, Grasso A, Chander SK, Purohit A, Reed MJ, Potter BV. Woo LW, et al. J Med Chem. 2003 Jul 17;46(15):3193-6. doi: 10.1021/jm034033b. J Med Chem. 2003. PMID: 12852749

9

Synthesis, in vitro and in vivo activity of benzophenone-based inhibitors of steroid sulfatase.

Hejaz HA, Woo LW, Purohit A, Reed MJ, Potter BV. Hejaz HA, et al. Among authors: woo lw. Bioorg Med Chem. 2004 May 15;12(10):2759-72. doi: 10.1016/j.bmc.2004.02.040. Bioorg Med Chem. 2004. PMID: 15110857

10

The role of steroid sulphatase in regulating the oestrogenicity of oestrogen sulphamates.

Chander SK, Purohit A, Woo LW, Potter BV, Reed MJ. Chander SK, et al. Among authors: woo lw. Biochem Biophys Res Commun. 2004 Sep 10;322(1):217-22. doi: 10.1016/j.bbrc.2004.07.108. Biochem Biophys Res Commun. 2004. PMID: 15313194

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