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Metabolism distribution and excretion of a matrix metalloproteinase-13 inhibitor, 4-[4-(4-fluorophenoxy)-benzenesulfonylamino]tetrahydropyran-4-carboxylic acid hydroxyamide (CP-544439), in rats and dogs: assessment of the metabolic profile of CP-544439 in plasma and urine of humans.
Dalvie D, Cosker T, Boyden T, Zhou S, Schroeder C, Potchoiba MJ. Dalvie D, et al. Among authors: potchoiba mj. Drug Metab Dispos. 2008 Sep;36(9):1869-83. doi: 10.1124/dmd.108.022566. Epub 2008 Jun 19. Drug Metab Dispos. 2008. PMID: 18566038
Metabolism, pharmacokinetics, and excretion of a cholesteryl ester transfer protein inhibitor, torcetrapib, in rats, monkeys, and mice: characterization of unusual and novel metabolites by high-resolution liquid chromatography-tandem mass spectrometry and 1H nuclear magnetic resonance.
Prakash C, Chen W, Rossulek M, Johnson K, Zhang C, O'Connell T, Potchoiba M, Dalvie D. Prakash C, et al. Drug Metab Dispos. 2008 Oct;36(10):2064-79. doi: 10.1124/dmd.108.022277. Epub 2008 Jul 24. Drug Metab Dispos. 2008. PMID: 18653742
Tissue Distribution and Elimination of Isavuconazole following Single and Repeat Oral-Dose Administration of Isavuconazonium Sulfate to Rats.
Schmitt-Hoffmann AH, Kato K, Townsend R, Potchoiba MJ, Hope WW, Andes D, Spickermann J, Schneidkraut MJ. Schmitt-Hoffmann AH, et al. Among authors: potchoiba mj. Antimicrob Agents Chemother. 2017 Nov 22;61(12):e01292-17. doi: 10.1128/AAC.01292-17. Print 2017 Dec. Antimicrob Agents Chemother. 2017. PMID: 28971866 Free PMC article.
23 results