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Drug binding to aromatic residues in the HERG channel pore cavity as possible explanation for acquired Long QT syndrome by antiparkinsonian drug budipine.
Scholz EP, Zitron E, Kiesecker C, Lueck S, Kathöfer S, Thomas D, Weretka S, Peth S, Kreye VA, Schoels W, Katus HA, Kiehn J, Karle CA. Scholz EP, et al. Among authors: kreye va. Naunyn Schmiedebergs Arch Pharmacol. 2003 Nov;368(5):404-14. doi: 10.1007/s00210-003-0805-5. Epub 2003 Oct 14. Naunyn Schmiedebergs Arch Pharmacol. 2003. PMID: 14557918
Inhibition of cardiac HERG potassium channels by the atypical antidepressant trazodone.
Zitron E, Kiesecker C, Scholz E, Lück S, Bloehs R, Kathöfer S, Thomas D, Kiehn J, Kreye VA, Katus HA, Schoels W, Karle CA. Zitron E, et al. Among authors: kreye va. Naunyn Schmiedebergs Arch Pharmacol. 2004 Aug;370(2):146-56. doi: 10.1007/s00210-004-0952-3. Epub 2004 Jul 29. Naunyn Schmiedebergs Arch Pharmacol. 2004. PMID: 15322737
62 results