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Targeting EGFR activity in blood vessels is sufficient to inhibit tumor growth and is accompanied by an increase in VEGFR-2 dependence in tumor endothelial cells.
Amin DN, Bielenberg DR, Lifshits E, Heymach JV, Klagsbrun M. Amin DN, et al. Among authors: klagsbrun m. Microvasc Res. 2008 May;76(1):15-22. doi: 10.1016/j.mvr.2008.01.002. Epub 2008 Mar 18. Microvasc Res. 2008. PMID: 18440031
We have previously reported that EGFR is not only expressed by the tumor cells but by the tumor endothelial cells (EC) as well (Amin, D. N., Hida, K., Bielenberg, D. R., Klagsbrun, M., 2006. Tumor endothelial cells express epidermal growth factor receptor (EGFR) but …
We have previously reported that EGFR is not only expressed by the tumor cells but by the tumor endothelial cells (EC) as well (Amin, D. N., …
Cytogenetic abnormalities of tumor-associated endothelial cells in human malignant tumors.
Akino T, Hida K, Hida Y, Tsuchiya K, Freedman D, Muraki C, Ohga N, Matsuda K, Akiyama K, Harabayashi T, Shinohara N, Nonomura K, Klagsbrun M, Shindoh M. Akino T, et al. Among authors: klagsbrun m. Am J Pathol. 2009 Dec;175(6):2657-67. doi: 10.2353/ajpath.2009.090202. Epub 2009 Oct 29. Am J Pathol. 2009. PMID: 19875502 Free PMC article.
Isolated tumor endothelial cells maintain specific character during long-term culture.
Matsuda K, Ohga N, Hida Y, Muraki C, Tsuchiya K, Kurosu T, Akino T, Shih SC, Totsuka Y, Klagsbrun M, Shindoh M, Hida K. Matsuda K, et al. Among authors: klagsbrun m. Biochem Biophys Res Commun. 2010 Apr 16;394(4):947-54. doi: 10.1016/j.bbrc.2010.03.089. Epub 2010 Mar 17. Biochem Biophys Res Commun. 2010. PMID: 20302845
270 results