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Orally administered targeted recombinant Beta-lactamase prevents ampicillin-induced selective pressure on the gut microbiota: a novel approach to reducing antimicrobial resistance.
Harmoinen J, Mentula S, Heikkilä M, van der Rest M, Rajala-Schultz PJ, Donskey CJ, Frias R, Koski P, Wickstrand N, Jousimies-Somer H, Westermarck E, Lindevall K. Harmoinen J, et al. Among authors: mentula s. Antimicrob Agents Chemother. 2004 Jan;48(1):75-9. doi: 10.1128/AAC.48.1.75-79.2004. Antimicrob Agents Chemother. 2004. PMID: 14693521 Free PMC article.
P1A recombinant beta-lactamase prevents emergence of antimicrobial resistance in gut microflora of healthy subjects during intravenous administration of ampicillin.
Tarkkanen AM, Heinonen T, Jõgi R, Mentula S, van der Rest ME, Donskey CJ, Kemppainen T, Gurbanov K, Nord CE. Tarkkanen AM, et al. Among authors: mentula s. Antimicrob Agents Chemother. 2009 Jun;53(6):2455-62. doi: 10.1128/AAC.00853-08. Epub 2009 Mar 23. Antimicrob Agents Chemother. 2009. PMID: 19307374 Free PMC article. Clinical Trial.
First isolation of Clostridium difficile PCR ribotype 027 in Finland.
Lyytikäinen O, Mentula S, Könönen E, Kotila S, Tarkka E, Anttila VJ, Mattila E, Kanerva M, Vaara M, Valtonen V. Lyytikäinen O, et al. Among authors: mentula s. Euro Surveill. 2007 Nov 8;12(11):E071108.2. doi: 10.2807/esw.12.45.03303-en. Euro Surveill. 2007. PMID: 18005648 Free article. No abstract available.
Detection of virulence genes of Clostridium difficile by multiplex PCR.
Antikainen J, Pasanen T, Mero S, Tarkka E, Kirveskari J, Kotila S, Mentula S, Könönen E, Virolainen-Julkunen AR, Vaara M, Tissari P. Antikainen J, et al. Among authors: mentula s. APMIS. 2009 Aug;117(8):607-13. doi: 10.1111/j.1600-0463.2009.02509.x. APMIS. 2009. PMID: 19664132
Reduction in Clostridium difficile infections in Finland, 2008-2010.
Kanerva M, Mentula S, Virolainen-Julkunen A, Kärki T, Möttönen T, Lyytikäinen O; Hospital Infection Surveillance Team. Kanerva M, et al. Among authors: mentula s. J Hosp Infect. 2013 Feb;83(2):127-31. doi: 10.1016/j.jhin.2012.09.021. Epub 2012 Nov 30. J Hosp Infect. 2013. PMID: 23201398
39 results