Guillen MJ - Search Results

1

Development of a liquid chromatography/tandem mass spectrometry assay for the quantification of PM00104, a novel antineoplastic agent, in mouse, rat, dog, and human plasma.

Yin J, Aviles P, Lee W, Ly C, Guillen MJ, Munt S, Cuevas C, Faircloth G. Yin J, et al. Among authors: guillen mj. Rapid Commun Mass Spectrom. 2005;19(5):689-95. doi: 10.1002/rcm.1848. Rapid Commun Mass Spectrom. 2005. PMID: 15702485

2

Validation of a sensitive assay for thiocoraline in mouse plasma using liquid chromatography-tandem mass spectrometry.

Yin J, Aviles P, Lee W, Ly C, Guillen MJ, Calvo P, Manzanares I, Faircloth G. Yin J, et al. Among authors: guillen mj. J Chromatogr B Analyt Technol Biomed Life Sci. 2003 Aug 25;794(1):89-98. doi: 10.1016/s1570-0232(03)00418-5. J Chromatogr B Analyt Technol Biomed Life Sci. 2003. PMID: 12888201

3

Quantitative analysis of Variolin analog (PM01218) in mouse and rat plasma by high-performance liquid chromatography/electrospray ionization tandem mass spectrometry.

Yin J, Aviles P, Ly C, Lee W, Guillen MJ, Munt S, Cuevas C, Faircloth G. Yin J, et al. Among authors: guillen mj. J Chromatogr B Analyt Technol Biomed Life Sci. 2006 Mar 7;832(2):268-73. doi: 10.1016/j.jchromb.2006.01.027. Epub 2006 Feb 21. J Chromatogr B Analyt Technol Biomed Life Sci. 2006. PMID: 16497567

4

Development of a liquid chromatography/tandem mass spectrometry assay for the quantification of PM02734, a novel antineoplastic agent, in dog plasma.

Yin J, Aviles P, Lee W, Ly C, Guillen MJ, Munt S, Cuevas C, Faircloth G. Yin J, et al. Among authors: guillen mj. Rapid Commun Mass Spectrom. 2006;20(18):2735-40. doi: 10.1002/rcm.2644. Rapid Commun Mass Spectrom. 2006. PMID: 16921565

5

Enhanced in vivo therapeutic efficacy of plitidepsin-loaded nanocapsules decorated with a new poly-aminoacid-PEG derivative.

Lollo G, Hervella P, Calvo P, Avilés P, Guillén MJ, Garcia-Fuentes M, Alonso MJ, Torres D. Lollo G, et al. Among authors: guillen mj. Int J Pharm. 2015 Apr 10;483(1-2):212-9. doi: 10.1016/j.ijpharm.2015.02.028. Epub 2015 Feb 11. Int J Pharm. 2015. PMID: 25681727

6

Development of a liquid chromatography/tandem mass spectrometry assay for the quantification of PM01183 (lurbinectedin), a novel antineoplastic agent, in mouse, rat, dog, Cynomolgus monkey and mini-pig plasma.

Pernice T, Bishop AG, Guillen MJ, Cuevas C, Aviles P. Pernice T, et al. Among authors: guillen mj. J Pharm Biomed Anal. 2016 May 10;123:37-41. doi: 10.1016/j.jpba.2016.01.043. Epub 2016 Jan 21. J Pharm Biomed Anal. 2016. PMID: 26871278

7

Lurbinectedin induces depletion of tumor-associated macrophages, an essential component of its in vivo synergism with gemcitabine, in pancreatic adenocarcinoma mouse models.

Céspedes MV, Guillén MJ, López-Casas PP, Sarno F, Gallardo A, Álamo P, Cuevas C, Hidalgo M, Galmarini CM, Allavena P, Avilés P, Mangues R. Céspedes MV, et al. Among authors: guillen mj. Dis Model Mech. 2016 Dec 1;9(12):1461-1471. doi: 10.1242/dmm.026369. Epub 2016 Oct 20. Dis Model Mech. 2016. PMID: 27780828 Free PMC article.

8

Improved pharmacokinetic profile of lipophilic anti-cancer drugs using ανβ3-targeted polyurethane-polyurea nanoparticles.

Rocas P, Fernández Y, García-Aranda N, Foradada L, Calvo P, Avilés P, Guillén MJ, Schwartz S Jr, Rocas J, Albericio F, Abasolo I. Rocas P, et al. Among authors: guillen mj. Nanomedicine. 2018 Feb;14(2):257-267. doi: 10.1016/j.nano.2017.10.009. Epub 2017 Nov 7. Nanomedicine. 2018. PMID: 29127040

9

MI130004, a Novel Antibody-Drug Conjugate Combining Trastuzumab with a Molecule of Marine Origin, Shows Outstanding In Vivo Activity against HER2-Expressing Tumors.

Avilés P, Domínguez JM, Guillén MJ, Muñoz-Alonso MJ, Mateo C, Rodriguez-Acebes R, Molina-Guijarro JM, Francesch A, Martínez-Leal JF, Munt S, Galmarini CM, Cuevas C. Avilés P, et al. Among authors: guillen mj. Mol Cancer Ther. 2018 Apr;17(4):786-794. doi: 10.1158/1535-7163.MCT-17-0795. Epub 2018 Feb 13. Mol Cancer Ther. 2018. PMID: 29440297

10

Development of a new method for the quantitation of metabolites in the absence of chemically synthetized authentic standards.

Altares R, Márquez Del Pino FM, Benedit G, Guillén MJ, Cuevas C, Pérez de la Cruz MA, Aviles P. Altares R, et al. Among authors: guillen mj. J Pharm Biomed Anal. 2019 May 30;169:70-74. doi: 10.1016/j.jpba.2019.01.027. Epub 2019 Feb 21. J Pharm Biomed Anal. 2019. PMID: 30831452

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