Nantz MH - Search Results

1

Phenylglycine and sulfonamide correctors of defective delta F508 and G551D cystic fibrosis transmembrane conductance regulator chloride-channel gating.

Pedemonte N, Sonawane ND, Taddei A, Hu J, Zegarra-Moran O, Suen YF, Robins LI, Dicus CW, Willenbring D, Nantz MH, Kurth MJ, Galietta LJ, Verkman AS. Pedemonte N, et al. Among authors: nantz mh. Mol Pharmacol. 2005 May;67(5):1797-807. doi: 10.1124/mol.105.010959. Epub 2005 Feb 18. Mol Pharmacol. 2005. PMID: 15722457

2

Benzoflavone activators of the cystic fibrosis transmembrane conductance regulator: towards a pharmacophore model for the nucleotide-binding domain.

Springsteel MF, Galietta LJ, Ma T, By K, Berger GO, Yang H, Dicus CW, Choung W, Quan C, Shelat AA, Guy RK, Verkman AS, Kurth MJ, Nantz MH. Springsteel MF, et al. Among authors: nantz mh. Bioorg Med Chem. 2003 Sep 1;11(18):4113-20. doi: 10.1016/s0968-0896(03)00435-8. Bioorg Med Chem. 2003. PMID: 12927873

3

Sulfamoyl-4-oxoquinoline-3-carboxamides: novel potentiators of defective DeltaF508-cystic fibrosis transmembrane conductance regulator chloride channel gating.

Suen YF, Robins L, Yang B, Verkman AS, Nantz MH, Kurth MJ. Suen YF, et al. Among authors: nantz mh. Bioorg Med Chem Lett. 2006 Feb;16(3):537-40. doi: 10.1016/j.bmcl.2005.10.050. Epub 2005 Nov 8. Bioorg Med Chem Lett. 2006. PMID: 16288863

4

Novel CFTR chloride channel activators identified by screening of combinatorial libraries based on flavone and benzoquinolizinium lead compounds.

Galietta LJ, Springsteel MF, Eda M, Niedzinski EJ, By K, Haddadin MJ, Kurth MJ, Nantz MH, Verkman AS. Galietta LJ, et al. Among authors: nantz mh. J Biol Chem. 2001 Jun 8;276(23):19723-8. doi: 10.1074/jbc.M101892200. Epub 2001 Mar 21. J Biol Chem. 2001. PMID: 11262417 Free article.

5

CFTR activation in human bronchial epithelial cells by novel benzoflavone and benzimidazolone compounds.

Caci E, Folli C, Zegarra-Moran O, Ma T, Springsteel MF, Sammelson RE, Nantz MH, Kurth MJ, Verkman AS, Galietta LJ. Caci E, et al. Among authors: nantz mh. Am J Physiol Lung Cell Mol Physiol. 2003 Jul;285(1):L180-8. doi: 10.1152/ajplung.00351.2002. Epub 2003 Mar 21. Am J Physiol Lung Cell Mol Physiol. 2003. PMID: 12651632 Free article.

6

The solid-phase Zincke reaction: preparation of omega-hydroxy pyridinium salts in the search for CFTR activation.

Eda M, Kurth MJ, Nantz MH. Eda M, et al. Among authors: nantz mh. J Org Chem. 2000 Aug 25;65(17):5131-5. doi: 10.1021/jo0001636. J Org Chem. 2000. PMID: 10993337

7

A novel route to fully substituted 1H-pyrazoles.

Suen YF, Hope H, Nantz MH, Haddadin MJ, Kurth MJ. Suen YF, et al. Among authors: nantz mh. J Org Chem. 2005 Oct 14;70(21):8468-71. doi: 10.1021/jo051319a. J Org Chem. 2005. PMID: 16209593

8

Structural determinants for activation and block of CFTR-mediated chloride currents by apigenin.

Illek B, Lizarzaburu ME, Lee V, Nantz MH, Kurth MJ, Fischer H. Illek B, et al. Among authors: nantz mh. Am J Physiol Cell Physiol. 2000 Dec;279(6):C1838-46. doi: 10.1152/ajpcell.2000.279.6.C1838. Am J Physiol Cell Physiol. 2000. PMID: 11078699 Free article.

9

Activation of CFTR by UCCF-029 and genistein.

Al-Nakkash L, Springsteel MF, Kurth MJ, Nantz MH. Al-Nakkash L, et al. Among authors: nantz mh. Bioorg Med Chem Lett. 2008 Jul 15;18(14):3874-7. doi: 10.1016/j.bmcl.2008.06.051. Epub 2008 Jun 19. Bioorg Med Chem Lett. 2008. PMID: 18595696

10

Transannular Anti-Michael Addition: Formation of 4H-Pyrazolo[5,1-c]thiazines.

Suen YF, Hope H, Nantz MH, Haddadin MJ, Kurth AM. Suen YF, et al. Among authors: nantz mh. Tetrahedron Lett. 2006 Nov 6;47(45):7893-7896. doi: 10.1016/j.tetlet.2006.09.015. Tetrahedron Lett. 2006. PMID: 21904417 Free PMC article.

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