Runyon SP - Search Results

1

Synthesis, structural identification, and ligand binding of tropane ring analogs of paroxetine and an unexpected aza-bicyclo[3.2.2]nonane rearrangement product.

Runyon SP, Burgess JP, Abraham P, Keverline-Frantz KI, Flippen-Anderson J, Deschamps J, Lewin AH, Navarro HA, Boja JW, Kuhar MJ, Carroll FI. Runyon SP, et al. Bioorg Med Chem. 2005 Apr 1;13(7):2439-49. doi: 10.1016/j.bmc.2005.01.046. Bioorg Med Chem. 2005. PMID: 15755646

2

Geometry-affinity relationships of the selective serotonin receptor ligand 9-(aminomethyl)-9,10-dihydroanthracene.

Runyon SP, Peddi S, Savage JE, Roth BL, Glennon RA, Westkaemper RB. Runyon SP, et al. J Med Chem. 2002 Apr 11;45(8):1656-64. doi: 10.1021/jm010354g. J Med Chem. 2002. PMID: 11931619

3

Monoamine transporter binding, locomotor activity, and drug discrimination properties of 3-(4-substituted-phenyl)tropane-2-carboxylic acid methyl ester isomers.

Carroll FI, Runyon SP, Abraham P, Navarro H, Kuhar MJ, Pollard GT, Howard JL. Carroll FI, et al. Among authors: runyon sp. J Med Chem. 2004 Dec 2;47(25):6401-9. doi: 10.1021/jm0401311. J Med Chem. 2004. PMID: 15566309

4

Dopamine transporter ligands: recent developments and therapeutic potential.

Runyon SP, Carroll FI. Runyon SP, et al. Curr Top Med Chem. 2006;6(17):1825-43. doi: 10.2174/156802606778249775. Curr Top Med Chem. 2006. PMID: 17017960 Review.

5

Identifying structural features on 1,1-diphenyl-hexahydro-oxazolo[3,4-a]pyrazin-3-ones critical for Neuropeptide S antagonist activity.

Zhang Y, Gilmour BP, Navarro HA, Runyon SP. Zhang Y, et al. Among authors: runyon sp. Bioorg Med Chem Lett. 2008 Jul 15;18(14):4064-7. doi: 10.1016/j.bmcl.2008.05.098. Epub 2008 Jun 12. Bioorg Med Chem Lett. 2008. PMID: 18555684 Free PMC article.

6

17beta-Nitro-5alpha-androstan-3alpha-ol and its 3beta-methyl derivative: neurosteroid analogs with potent anticonvulsant and anxiolytic activities.

Runyon SP, Orr M, Navarro HA, Kepler JA, Rogawski MA, Kaminski RM, Cook CE. Runyon SP, et al. Eur J Pharmacol. 2009 Sep 1;617(1-3):68-73. doi: 10.1016/j.ejphar.2009.06.052. Epub 2009 Jul 2. Eur J Pharmacol. 2009. PMID: 19577558 Free PMC article.

7

Analogues of (3R)-7-hydroxy-N-[(1S)-1-{[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl}-2-methylpropyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide (JDTic). Synthesis and in vitro and in vivo opioid receptor antagonist activity.

Runyon SP, Brieaddy LE, Mascarella SW, Thomas JB, Navarro HA, Howard JL, Pollard GT, Carroll FI. Runyon SP, et al. J Med Chem. 2010 Jul 22;53(14):5290-301. doi: 10.1021/jm1004978. J Med Chem. 2010. PMID: 20568781 Free PMC article.

8

1-Substituted 4-(3-Hydroxyphenyl)piperazines Are Pure Opioid Receptor Antagonists.

Carroll FI, Cueva JP, Thomas JB, Mascarella SW, Runyon SP, Navarro HA. Carroll FI, et al. Among authors: runyon sp. ACS Med Chem Lett. 2010 Oct 14;1(7):365-369. doi: 10.1021/ml100126b. ACS Med Chem Lett. 2010. PMID: 21116435 Free PMC article.

9

Diaryl urea analogues of SB-334867 as orexin-1 receptor antagonists.

Perrey DA, Gilmour BP, Runyon SP, Thomas BF, Zhang Y. Perrey DA, et al. Among authors: runyon sp. Bioorg Med Chem Lett. 2011 May 15;21(10):2980-5. doi: 10.1016/j.bmcl.2011.03.048. Epub 2011 Mar 21. Bioorg Med Chem Lett. 2011. PMID: 21478014 Free PMC article.

10

Hydrolytic instability of the important orexin 1 receptor antagonist SB-334867: possible confounding effects on in vivo and in vitro studies.

McElhinny CJ Jr, Lewin AH, Mascarella SW, Runyon S, Brieaddy L, Carroll FI. McElhinny CJ Jr, et al. Bioorg Med Chem Lett. 2012 Nov 1;22(21):6661-4. doi: 10.1016/j.bmcl.2012.08.109. Epub 2012 Sep 7. Bioorg Med Chem Lett. 2012. PMID: 23031594

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