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Prophylactic effect of ensitrelvir in mice infected with SARS-CoV-2.
Nobori H, Baba K, Kuroda T, Baba K, Matsumoto K, Yoshida S, Watari R, Tachibana Y, Kato T, Fukao K. Nobori H, et al. Antiviral Res. 2024 Apr;224:105852. doi: 10.1016/j.antiviral.2024.105852. Epub 2024 Feb 28. Antiviral Res. 2024. PMID: 38428748 Free article.
Combination therapy with oral antiviral and anti-inflammatory drugs improves the efficacy of delayed treatment in a COVID-19 hamster model.
Sasaki M, Sugi T, Iida S, Hirata Y, Kusakabe S, Konishi K, Itakura Y, Tabata K, Kishimoto M, Kobayashi H, Ariizumi T, Intaruck K, Nobori H, Toba S, Sato A, Matsuno K, Yamagishi J, Suzuki T, Hall WW, Orba Y, Sawa H. Sasaki M, et al. Among authors: nobori h. EBioMedicine. 2024 Jan;99:104950. doi: 10.1016/j.ebiom.2023.104950. Epub 2023 Dec 30. EBioMedicine. 2024. PMID: 38159532 Free PMC article.
2-thiouridine is a broad-spectrum antiviral nucleoside analogue against positive-strand RNA viruses.
Uemura K, Nobori H, Sato A, Toba S, Kusakabe S, Sasaki M, Tabata K, Matsuno K, Maeda N, Ito S, Tanaka M, Anraku Y, Kita S, Ishii M, Kanamitsu K, Orba Y, Matsuura Y, Hall WW, Sawa H, Kida H, Matsuda A, Maenaka K. Uemura K, et al. Among authors: nobori h. Proc Natl Acad Sci U S A. 2023 Oct 17;120(42):e2304139120. doi: 10.1073/pnas.2304139120. Epub 2023 Oct 13. Proc Natl Acad Sci U S A. 2023. PMID: 37831739 Free PMC article.
Efficacy comparison of 3CL protease inhibitors ensitrelvir and nirmatrelvir against SARS-CoV-2 in vitro and in vivo.
Kuroda T, Nobori H, Fukao K, Baba K, Matsumoto K, Yoshida S, Tanaka Y, Watari R, Oka R, Kasai Y, Inoue K, Kawashima S, Shimba A, Hayasaki-Kajiwara Y, Tanimura M, Zhang Q, Tachibana Y, Kato T, Shishido T. Kuroda T, et al. Among authors: nobori h. J Antimicrob Chemother. 2023 Apr 3;78(4):946-952. doi: 10.1093/jac/dkad027. J Antimicrob Chemother. 2023. PMID: 36760083 Free PMC article.
Ensitrelvir is effective against SARS-CoV-2 3CL protease mutants circulating globally.
Kawashima S, Matsui Y, Adachi T, Morikawa Y, Inoue K, Takebayashi S, Nobori H, Rokushima M, Tachibana Y, Kato T. Kawashima S, et al. Among authors: nobori h. Biochem Biophys Res Commun. 2023 Feb 19;645:132-136. doi: 10.1016/j.bbrc.2023.01.040. Epub 2023 Jan 14. Biochem Biophys Res Commun. 2023. PMID: 36689809 Free PMC article.
26 results