Bornmann WG - Search Results

1

Development of beta-lapachone prodrugs for therapy against human cancer cells with elevated NAD(P)H:quinone oxidoreductase 1 levels.

Reinicke KE, Bey EA, Bentle MS, Pink JJ, Ingalls ST, Hoppel CL, Misico RI, Arzac GM, Burton G, Bornmann WG, Sutton D, Gao J, Boothman DA. Reinicke KE, et al. Among authors: bornmann wg. Clin Cancer Res. 2005 Apr 15;11(8):3055-64. doi: 10.1158/1078-0432.CCR-04-2185. Clin Cancer Res. 2005. PMID: 15837761

2

Intratumoral delivery of beta-lapachone via polymer implants for prostate cancer therapy.

Dong Y, Chin SF, Blanco E, Bey EA, Kabbani W, Xie XJ, Bornmann WG, Boothman DA, Gao J. Dong Y, et al. Among authors: bornmann wg. Clin Cancer Res. 2009 Jan 1;15(1):131-9. doi: 10.1158/1078-0432.CCR-08-1691. Clin Cancer Res. 2009. PMID: 19118040 Free PMC article.

3

Beta-lapachone micellar nanotherapeutics for non-small cell lung cancer therapy.

Blanco E, Bey EA, Khemtong C, Yang SG, Setti-Guthi J, Chen H, Kessinger CW, Carnevale KA, Bornmann WG, Boothman DA, Gao J. Blanco E, et al. Among authors: bornmann wg. Cancer Res. 2010 May 15;70(10):3896-904. doi: 10.1158/0008-5472.CAN-09-3995. Epub 2010 May 11. Cancer Res. 2010. PMID: 20460521 Free PMC article.

4

Modulating endogenous NQO1 levels identifies key regulatory mechanisms of action of β-lapachone for pancreatic cancer therapy.

Li LS, Bey EA, Dong Y, Meng J, Patra B, Yan J, Xie XJ, Brekken RA, Barnett CC, Bornmann WG, Gao J, Boothman DA. Li LS, et al. Among authors: bornmann wg. Clin Cancer Res. 2011 Jan 15;17(2):275-85. doi: 10.1158/1078-0432.CCR-10-1983. Epub 2011 Jan 11. Clin Cancer Res. 2011. PMID: 21224367 Free PMC article.

5

An NQO1- and PARP-1-mediated cell death pathway induced in non-small-cell lung cancer cells by beta-lapachone.

Bey EA, Bentle MS, Reinicke KE, Dong Y, Yang CR, Girard L, Minna JD, Bornmann WG, Gao J, Boothman DA. Bey EA, et al. Among authors: bornmann wg. Proc Natl Acad Sci U S A. 2007 Jul 10;104(28):11832-7. doi: 10.1073/pnas.0702176104. Epub 2007 Jul 3. Proc Natl Acad Sci U S A. 2007. PMID: 17609380 Free PMC article.

6

beta-Lapachone-induced apoptosis in human prostate cancer cells: involvement of NQO1/xip3.

Planchon SM, Pink JJ, Tagliarino C, Bornmann WG, Varnes ME, Boothman DA. Planchon SM, et al. Among authors: bornmann wg. Exp Cell Res. 2001 Jul 1;267(1):95-106. doi: 10.1006/excr.2001.5234. Exp Cell Res. 2001. PMID: 11412042

7

Efficacy of beta-lapachone in pancreatic cancer treatment: exploiting the novel, therapeutic target NQO1.

Ough M, Lewis A, Bey EA, Gao J, Ritchie JM, Bornmann W, Boothman DA, Oberley LW, Cullen JJ. Ough M, et al. Cancer Biol Ther. 2005 Jan;4(1):95-102. doi: 10.4161/cbt.4.1.1382. Epub 2005 Jan 15. Cancer Biol Ther. 2005. PMID: 15662131

8

Enhancement of solubility and bioavailability of beta-lapachone using cyclodextrin inclusion complexes.

Nasongkla N, Wiedmann AF, Bruening A, Beman M, Ray D, Bornmann WG, Boothman DA, Gao J. Nasongkla N, et al. Among authors: bornmann wg. Pharm Res. 2003 Oct;20(10):1626-33. doi: 10.1023/a:1026143519395. Pharm Res. 2003. PMID: 14620518

9

Susceptibility of cancer cells to beta-lapachone is enhanced by ionizing radiation.

Park HJ, Ahn KJ, Ahn SD, Choi E, Lee SW, Williams B, Kim EJ, Griffin R, Bey EA, Bornmann WG, Gao J, Park HJ, Boothman DA, Song CW. Park HJ, et al. Among authors: bornmann wg. Int J Radiat Oncol Biol Phys. 2005 Jan 1;61(1):212-9. doi: 10.1016/j.ijrobp.2004.09.018. Int J Radiat Oncol Biol Phys. 2005. PMID: 15629614

10

Induction of apoptosis in MCF-7:WS8 breast cancer cells by beta-lapachone.

Wuerzberger SM, Pink JJ, Planchon SM, Byers KL, Bornmann WG, Boothman DA. Wuerzberger SM, et al. Among authors: bornmann wg. Cancer Res. 1998 May 1;58(9):1876-85. Cancer Res. 1998. PMID: 9581828

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