Gorlatov S - Search Results

1

Development of a humanized monoclonal antibody with therapeutic potential against West Nile virus.

Oliphant T, Engle M, Nybakken GE, Doane C, Johnson S, Huang L, Gorlatov S, Mehlhop E, Marri A, Chung KM, Ebel GD, Kramer LD, Fremont DH, Diamond MS. Oliphant T, et al. Among authors: gorlatov s. Nat Med. 2005 May;11(5):522-30. doi: 10.1038/nm1240. Epub 2005 Apr 24. Nat Med. 2005. PMID: 15852016 Free PMC article.

2

Complement protein C1q reduces the stoichiometric threshold for antibody-mediated neutralization of West Nile virus.

Mehlhop E, Nelson S, Jost CA, Gorlatov S, Johnson S, Fremont DH, Diamond MS, Pierson TC. Mehlhop E, et al. Among authors: gorlatov s. Cell Host Microbe. 2009 Oct 22;6(4):381-91. doi: 10.1016/j.chom.2009.09.003. Cell Host Microbe. 2009. PMID: 19837377 Free PMC article.

3

Development of a highly protective combination monoclonal antibody therapy against Chikungunya virus.

Pal P, Dowd KA, Brien JD, Edeling MA, Gorlatov S, Johnson S, Lee I, Akahata W, Nabel GJ, Richter MK, Smit JM, Fremont DH, Pierson TC, Heise MT, Diamond MS. Pal P, et al. Among authors: gorlatov s. PLoS Pathog. 2013;9(4):e1003312. doi: 10.1371/journal.ppat.1003312. Epub 2013 Apr 18. PLoS Pathog. 2013. PMID: 23637602 Free PMC article.

4

Generation and analysis of novel plant-derived antibody-based therapeutic molecules against West Nile virus.

He J, Lai H, Engle M, Gorlatov S, Gruber C, Steinkellner H, Diamond MS, Chen Q. He J, et al. Among authors: gorlatov s. PLoS One. 2014 Mar 27;9(3):e93541. doi: 10.1371/journal.pone.0093541. eCollection 2014. PLoS One. 2014. PMID: 24675995 Free PMC article.

5

Monoclonal antibody produced in plants efficiently treats West Nile virus infection in mice.

Lai H, Engle M, Fuchs A, Keller T, Johnson S, Gorlatov S, Diamond MS, Chen Q. Lai H, et al. Among authors: gorlatov s. Proc Natl Acad Sci U S A. 2010 Feb 9;107(6):2419-24. doi: 10.1073/pnas.0914503107. Epub 2010 Feb 1. Proc Natl Acad Sci U S A. 2010. PMID: 20133644 Free PMC article.

6

Structural and functional characterization of an anti-West Nile virus monoclonal antibody and its single-chain variant produced in glycoengineered plants.

Lai H, He J, Hurtado J, Stahnke J, Fuchs A, Mehlhop E, Gorlatov S, Loos A, Diamond MS, Chen Q. Lai H, et al. Among authors: gorlatov s. Plant Biotechnol J. 2014 Oct;12(8):1098-107. doi: 10.1111/pbi.12217. Epub 2014 Jun 29. Plant Biotechnol J. 2014. PMID: 24975464 Free PMC article.

7

Development of an Fc-enhanced anti-B7-H3 monoclonal antibody with potent antitumor activity.

Loo D, Alderson RF, Chen FZ, Huang L, Zhang W, Gorlatov S, Burke S, Ciccarone V, Li H, Yang Y, Son T, Chen Y, Easton AN, Li JC, Rillema JR, Licea M, Fieger C, Liang TW, Mather JP, Koenig S, Stewart SJ, Johnson S, Bonvini E, Moore PA. Loo D, et al. Among authors: gorlatov s. Clin Cancer Res. 2012 Jul 15;18(14):3834-45. doi: 10.1158/1078-0432.CCR-12-0715. Epub 2012 May 21. Clin Cancer Res. 2012. PMID: 22615450

8

Fc optimization of therapeutic antibodies enhances their ability to kill tumor cells in vitro and controls tumor expansion in vivo via low-affinity activating Fcgamma receptors.

Stavenhagen JB, Gorlatov S, Tuaillon N, Rankin CT, Li H, Burke S, Huang L, Vijh S, Johnson S, Bonvini E, Koenig S. Stavenhagen JB, et al. Among authors: gorlatov s. Cancer Res. 2007 Sep 15;67(18):8882-90. doi: 10.1158/0008-5472.CAN-07-0696. Cancer Res. 2007. PMID: 17875730

9

Enhancing the potency of therapeutic monoclonal antibodies via Fc optimization.

Stavenhagen JB, Gorlatov S, Tuaillon N, Rankin CT, Li H, Burke S, Huang L, Johnson S, Koenig S, Bonvini E. Stavenhagen JB, et al. Among authors: gorlatov s. Adv Enzyme Regul. 2008;48:152-64. doi: 10.1016/j.advenzreg.2007.11.011. Epub 2007 Dec 3. Adv Enzyme Regul. 2008. PMID: 18177741 No abstract available.

10

Anti-tumor activity and toxicokinetics analysis of MGAH22, an anti-HER2 monoclonal antibody with enhanced Fcγ receptor binding properties.

Nordstrom JL, Gorlatov S, Zhang W, Yang Y, Huang L, Burke S, Li H, Ciccarone V, Zhang T, Stavenhagen J, Koenig S, Stewart SJ, Moore PA, Johnson S, Bonvini E. Nordstrom JL, et al. Among authors: gorlatov s. Breast Cancer Res. 2011;13(6):R123. doi: 10.1186/bcr3069. Epub 2011 Nov 30. Breast Cancer Res. 2011. PMID: 22129105 Free PMC article.

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